Aptamer-assisted tumor localization of bacteria for enhanced biotherapy

Bacteria-based therapy has shown promise for cancer treatment. To enhance tumor accumulation, here the authors describe the design of tumor specific aptamer-conjugated bacteria, to improve intratumor localization and enhance therapeutic efficacy.

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Autores principales:	Zhongmin Geng, Zhenping Cao, Rui Liu, Ke Liu, Jinyao Liu, Weihong Tan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eae6b61d0b664e7a967ca3213ea808d7
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spelling	oai:doaj.org-article:eae6b61d0b664e7a967ca3213ea808d72021-11-21T12:35:14ZAptamer-assisted tumor localization of bacteria for enhanced biotherapy10.1038/s41467-021-26956-82041-1723https://doaj.org/article/eae6b61d0b664e7a967ca3213ea808d72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26956-8https://doaj.org/toc/2041-1723Bacteria-based therapy has shown promise for cancer treatment. To enhance tumor accumulation, here the authors describe the design of tumor specific aptamer-conjugated bacteria, to improve intratumor localization and enhance therapeutic efficacy.Zhongmin GengZhenping CaoRui LiuKe LiuJinyao LiuWeihong TanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhongmin Geng Zhenping Cao Rui Liu Ke Liu Jinyao Liu Weihong Tan Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
description	Bacteria-based therapy has shown promise for cancer treatment. To enhance tumor accumulation, here the authors describe the design of tumor specific aptamer-conjugated bacteria, to improve intratumor localization and enhance therapeutic efficacy.
format	article
author	Zhongmin Geng Zhenping Cao Rui Liu Ke Liu Jinyao Liu Weihong Tan
author_facet	Zhongmin Geng Zhenping Cao Rui Liu Ke Liu Jinyao Liu Weihong Tan
author_sort	Zhongmin Geng
title	Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
title_short	Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
title_full	Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
title_fullStr	Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
title_full_unstemmed	Aptamer-assisted tumor localization of bacteria for enhanced biotherapy
title_sort	aptamer-assisted tumor localization of bacteria for enhanced biotherapy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eae6b61d0b664e7a967ca3213ea808d7
work_keys_str_mv	AT zhongmingeng aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy AT zhenpingcao aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy AT ruiliu aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy AT keliu aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy AT jinyaoliu aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy AT weihongtan aptamerassistedtumorlocalizationofbacteriaforenhancedbiotherapy
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Aptamer-assisted tumor localization of bacteria for enhanced biotherapy

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