Aptamer-assisted tumor localization of bacteria for enhanced biotherapy

Bacteria-based therapy has shown promise for cancer treatment. To enhance tumor accumulation, here the authors describe the design of tumor specific aptamer-conjugated bacteria, to improve intratumor localization and enhance therapeutic efficacy.

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Bibliographic Details
Main Authors: Zhongmin Geng, Zhenping Cao, Rui Liu, Ke Liu, Jinyao Liu, Weihong Tan
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/eae6b61d0b664e7a967ca3213ea808d7
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