Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast

Diterpenes are plant products with high antioxidant properties and potential application as food additives and therapeutics. Here, the authors describe the complete biosynthetic pathway of carnosic acid and reconstruct it in yeast, opening the way to metabolic engineering of phenolic diterpenes.

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Autores principales:	Ulschan Scheler, Wolfgang Brandt, Andrea Porzel, Kathleen Rothe, David Manzano, Dragana Božić, Dimitra Papaefthimiou, Gerd Ulrich Balcke, Anja Henning, Swanhild Lohse, Sylvestre Marillonnet, Angelos K. Kanellis, Albert Ferrer, Alain Tissier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eae7c8f3c7ec41be8b6d83b1c48ac17f
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spelling	oai:doaj.org-article:eae7c8f3c7ec41be8b6d83b1c48ac17f2021-12-02T16:49:25ZElucidation of the biosynthesis of carnosic acid and its reconstitution in yeast10.1038/ncomms129422041-1723https://doaj.org/article/eae7c8f3c7ec41be8b6d83b1c48ac17f2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12942https://doaj.org/toc/2041-1723Diterpenes are plant products with high antioxidant properties and potential application as food additives and therapeutics. Here, the authors describe the complete biosynthetic pathway of carnosic acid and reconstruct it in yeast, opening the way to metabolic engineering of phenolic diterpenes.Ulschan SchelerWolfgang BrandtAndrea PorzelKathleen RotheDavid ManzanoDragana BožićDimitra PapaefthimiouGerd Ulrich BalckeAnja HenningSwanhild LohseSylvestre MarillonnetAngelos K. KanellisAlbert FerrerAlain TissierNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ulschan Scheler Wolfgang Brandt Andrea Porzel Kathleen Rothe David Manzano Dragana Božić Dimitra Papaefthimiou Gerd Ulrich Balcke Anja Henning Swanhild Lohse Sylvestre Marillonnet Angelos K. Kanellis Albert Ferrer Alain Tissier Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
description	Diterpenes are plant products with high antioxidant properties and potential application as food additives and therapeutics. Here, the authors describe the complete biosynthetic pathway of carnosic acid and reconstruct it in yeast, opening the way to metabolic engineering of phenolic diterpenes.
format	article
author	Ulschan Scheler Wolfgang Brandt Andrea Porzel Kathleen Rothe David Manzano Dragana Božić Dimitra Papaefthimiou Gerd Ulrich Balcke Anja Henning Swanhild Lohse Sylvestre Marillonnet Angelos K. Kanellis Albert Ferrer Alain Tissier
author_facet	Ulschan Scheler Wolfgang Brandt Andrea Porzel Kathleen Rothe David Manzano Dragana Božić Dimitra Papaefthimiou Gerd Ulrich Balcke Anja Henning Swanhild Lohse Sylvestre Marillonnet Angelos K. Kanellis Albert Ferrer Alain Tissier
author_sort	Ulschan Scheler
title	Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
title_short	Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
title_full	Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
title_fullStr	Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
title_full_unstemmed	Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
title_sort	elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/eae7c8f3c7ec41be8b6d83b1c48ac17f
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Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast

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