A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up

Li-Qun Wang,1 Wai Tong Chien,2 Lai King Yip,2 Thanos Karatzias3 1School of Nursing, Jilin Medical College, Jilin, 2School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, People’s Republic of China; 3Faculty of Health, Life and Social Sciences, Edinburgh...

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Autores principales:	Wang LQ, Chien WT, Yip LK, Karatzias T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Mindfulness intervention Psycho-education Randomized controlled trial Psychotic symptoms Re-hospitalization Schizophrenia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/eae803333ad84ae5876ab4c749124c57
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spelling	oai:doaj.org-article:eae803333ad84ae5876ab4c749124c572021-12-02T07:52:25ZA randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up1178-2021https://doaj.org/article/eae803333ad84ae5876ab4c749124c572016-12-01T00:00:00Zhttps://www.dovepress.com/a-randomized-controlled-trial-of-a-mindfulness-based-intervention-prog-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Li-Qun Wang,1 Wai Tong Chien,2 Lai King Yip,2 Thanos Karatzias3 1School of Nursing, Jilin Medical College, Jilin, 2School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, People’s Republic of China; 3Faculty of Health, Life and Social Sciences, Edinburgh Napier University, Edinburgh, Scotland, UK Abstract: Mindfulness-based interventions have been increasingly evidenced to be effective in different mental illnesses but limited in schizophrenia. This single-blind, multisite randomized controlled trial tested the effects of a mindfulness-based psychoeducation group program (MPGP in addition to usual care) versus a conventional psychoeducation group program (CPGP) versus treatment-as-usual (TAU) alone, in schizophrenia spectrum disorders over a 6-month follow-up. In each of the two study sites (outpatient clinics), 69 outpatients with schizophrenia or its subtypes (N=138) were randomly allocated to one of the three study groups (n=46) after baseline measurements and underwent 6 months of intervention. Primary outcomes including patients’ mental state and rehospitalization rate and other secondary outcomes were assessed at entry and at 1 week and 6 months. One hundred and thirty-one (95%) participants completed the interventions assigned and one to two post-tests. Multivariate analyses of variance (followed by univariate contrast tests) indicated that the MPGP participants reported greater reductions in their psychotic symptoms (P=0.003) and length/duration of rehospitalizations (P=0.005) at 6-month follow-up. Patients in the MPGP group also reported greater improvements in their insight into illness/treatment (P=0.0008) and level of functioning (P=0.002) than the CPGP and TAU alone at the 1-week and 6-month follow-up. Overall, the findings suggest that MPGP can be useful in improving the short- to medium-term clinical outcomes of outpatients with schizophrenia spectrum disorders, not only in terms of their mental state and risk of relapse but also their insight into illness/treatment and psychosocial functioning. Keywords: mindfulness intervention, psychoeducation, functioning, insight into illness, psychotic symptoms, rehospitalization, schizophreniaWang LQChien WTYip LKKaratzias TDove Medical PressarticleMindfulness interventionPsycho-educationRandomized controlled trialPsychotic symptomsRe-hospitalizationSchizophreniaNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 12, Pp 3097-3110 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Mindfulness intervention Psycho-education Randomized controlled trial Psychotic symptoms Re-hospitalization Schizophrenia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Mindfulness intervention Psycho-education Randomized controlled trial Psychotic symptoms Re-hospitalization Schizophrenia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wang LQ Chien WT Yip LK Karatzias T A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
description	Li-Qun Wang,1 Wai Tong Chien,2 Lai King Yip,2 Thanos Karatzias3 1School of Nursing, Jilin Medical College, Jilin, 2School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, People’s Republic of China; 3Faculty of Health, Life and Social Sciences, Edinburgh Napier University, Edinburgh, Scotland, UK Abstract: Mindfulness-based interventions have been increasingly evidenced to be effective in different mental illnesses but limited in schizophrenia. This single-blind, multisite randomized controlled trial tested the effects of a mindfulness-based psychoeducation group program (MPGP in addition to usual care) versus a conventional psychoeducation group program (CPGP) versus treatment-as-usual (TAU) alone, in schizophrenia spectrum disorders over a 6-month follow-up. In each of the two study sites (outpatient clinics), 69 outpatients with schizophrenia or its subtypes (N=138) were randomly allocated to one of the three study groups (n=46) after baseline measurements and underwent 6 months of intervention. Primary outcomes including patients’ mental state and rehospitalization rate and other secondary outcomes were assessed at entry and at 1 week and 6 months. One hundred and thirty-one (95%) participants completed the interventions assigned and one to two post-tests. Multivariate analyses of variance (followed by univariate contrast tests) indicated that the MPGP participants reported greater reductions in their psychotic symptoms (P=0.003) and length/duration of rehospitalizations (P=0.005) at 6-month follow-up. Patients in the MPGP group also reported greater improvements in their insight into illness/treatment (P=0.0008) and level of functioning (P=0.002) than the CPGP and TAU alone at the 1-week and 6-month follow-up. Overall, the findings suggest that MPGP can be useful in improving the short- to medium-term clinical outcomes of outpatients with schizophrenia spectrum disorders, not only in terms of their mental state and risk of relapse but also their insight into illness/treatment and psychosocial functioning. Keywords: mindfulness intervention, psychoeducation, functioning, insight into illness, psychotic symptoms, rehospitalization, schizophrenia
format	article
author	Wang LQ Chien WT Yip LK Karatzias T
author_facet	Wang LQ Chien WT Yip LK Karatzias T
author_sort	Wang LQ
title	A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
title_short	A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
title_full	A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
title_fullStr	A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
title_full_unstemmed	A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
title_sort	randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/eae803333ad84ae5876ab4c749124c57
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A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up

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