A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes

The Oxford Nanopore system is capable of direct RNA sequencing but complex transcriptome analysis still remains to be thoroughly investigated. Here the authors perform sequencing of native RNA as well as cDNA to characterise the strengths and weaknesses of the system.

Guardado en:

Detalles Bibliográficos
Autores principales:	Charlotte Soneson, Yao Yao, Anna Bratus-Neuenschwander, Andrea Patrignani, Mark D. Robinson, Shobbir Hussain
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eae8ae3736ef4116884b5e7f579e752f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eae8ae3736ef4116884b5e7f579e752f
record_format	dspace
spelling	oai:doaj.org-article:eae8ae3736ef4116884b5e7f579e752f2021-12-02T17:33:11ZA comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes10.1038/s41467-019-11272-z2041-1723https://doaj.org/article/eae8ae3736ef4116884b5e7f579e752f2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11272-zhttps://doaj.org/toc/2041-1723The Oxford Nanopore system is capable of direct RNA sequencing but complex transcriptome analysis still remains to be thoroughly investigated. Here the authors perform sequencing of native RNA as well as cDNA to characterise the strengths and weaknesses of the system.Charlotte SonesonYao YaoAnna Bratus-NeuenschwanderAndrea PatrignaniMark D. RobinsonShobbir HussainNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Charlotte Soneson Yao Yao Anna Bratus-Neuenschwander Andrea Patrignani Mark D. Robinson Shobbir Hussain A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
description	The Oxford Nanopore system is capable of direct RNA sequencing but complex transcriptome analysis still remains to be thoroughly investigated. Here the authors perform sequencing of native RNA as well as cDNA to characterise the strengths and weaknesses of the system.
format	article
author	Charlotte Soneson Yao Yao Anna Bratus-Neuenschwander Andrea Patrignani Mark D. Robinson Shobbir Hussain
author_facet	Charlotte Soneson Yao Yao Anna Bratus-Neuenschwander Andrea Patrignani Mark D. Robinson Shobbir Hussain
author_sort	Charlotte Soneson
title	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
title_short	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
title_full	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
title_fullStr	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
title_full_unstemmed	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
title_sort	comprehensive examination of nanopore native rna sequencing for characterization of complex transcriptomes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/eae8ae3736ef4116884b5e7f579e752f
work_keys_str_mv	AT charlottesoneson acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT yaoyao acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT annabratusneuenschwander acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT andreapatrignani acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT markdrobinson acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT shobbirhussain acomprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT charlottesoneson comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT yaoyao comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT annabratusneuenschwander comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT andreapatrignani comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT markdrobinson comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes AT shobbirhussain comprehensiveexaminationofnanoporenativernasequencingforcharacterizationofcomplextranscriptomes
_version_	1718380035042181120

A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes

Ejemplares similares