A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes

The Oxford Nanopore system is capable of direct RNA sequencing but complex transcriptome analysis still remains to be thoroughly investigated. Here the authors perform sequencing of native RNA as well as cDNA to characterise the strengths and weaknesses of the system.

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Auteurs principaux: Charlotte Soneson, Yao Yao, Anna Bratus-Neuenschwander, Andrea Patrignani, Mark D. Robinson, Shobbir Hussain
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/eae8ae3736ef4116884b5e7f579e752f
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