Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vita...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN FA |
| Publicado: |
Babol University of Medical Sciences
2011
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/eaeb2eea7aa94ef4a3683ecda4bb0298 |
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| Sumario: | BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it. METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change. CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia. |
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