Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia

BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vita...

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Autores principales:	M Alvandipour, P Tayebi, R Alizadeh Navaie, H Khodabakhshi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2011
Materias:	cyclic mastalgia vitamin e primrose oil Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/eaeb2eea7aa94ef4a3683ecda4bb0298
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spelling	oai:doaj.org-article:eaeb2eea7aa94ef4a3683ecda4bb02982021-11-10T08:56:27ZComparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia1561-41072251-7170https://doaj.org/article/eaeb2eea7aa94ef4a3683ecda4bb02982011-03-01T00:00:00Zhttp://jbums.org/article-1-3734-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it. METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change. CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia.M AlvandipourP TayebiR Alizadeh NavaieH KhodabakhshiBabol University of Medical Sciencesarticlecyclic mastalgiavitamin eprimrose oilMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 2, Pp 7-11 (2011)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	cyclic mastalgia vitamin e primrose oil Medicine R Medicine (General) R5-920
spellingShingle	cyclic mastalgia vitamin e primrose oil Medicine R Medicine (General) R5-920 M Alvandipour P Tayebi R Alizadeh Navaie H Khodabakhshi Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
description	BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it. METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change. CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia.
format	article
author	M Alvandipour P Tayebi R Alizadeh Navaie H Khodabakhshi
author_facet	M Alvandipour P Tayebi R Alizadeh Navaie H Khodabakhshi
author_sort	M Alvandipour
title	Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_short	Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_full	Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_fullStr	Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_full_unstemmed	Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_sort	comparison between effect of evening primrose oil and vitamin e in treatment of cyclic mastalgia
publisher	Babol University of Medical Sciences
publishDate	2011
url	https://doaj.org/article/eaeb2eea7aa94ef4a3683ecda4bb0298
work_keys_str_mv	AT malvandipour comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia AT ptayebi comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia AT ralizadehnavaie comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia AT hkhodabakhshi comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia
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Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia

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