Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?

Abstract To evaluate acoustic radiation force impulse (ARFI) inthe differential diagnosis of small (≤20 mm) solid breast lesions and identify the most efficient ARFI parameters. Conventional ultrasonography and ARFIwere performed in 120 patients with 121 small solid breast lesions. The area ratios (...

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Autores principales:	Si-Da Wang, Lei Wang, Zhi-Xian Li, Kang-Lai Wei, Xin-Hong Liao, Yuan-Yuan Chen, Xue Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/eafc4105395940279dbb8301a426786b
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spelling	oai:doaj.org-article:eafc4105395940279dbb8301a426786b2021-12-02T11:41:12ZDifferential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?10.1038/s41598-017-08004-y2045-2322https://doaj.org/article/eafc4105395940279dbb8301a426786b2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08004-yhttps://doaj.org/toc/2045-2322Abstract To evaluate acoustic radiation force impulse (ARFI) inthe differential diagnosis of small (≤20 mm) solid breast lesions and identify the most efficient ARFI parameters. Conventional ultrasonography and ARFIwere performed in 120 patients with 121 small solid breast lesions. The area ratios (ARs) of the lesion on virtual touch tissue compared to B-mode were calculated. The shear wave velocity of the inner (SWVi) and boundary (SWVb) of the lesions and surrounding fatty tissue (SWVf) was measured. The ratio of SWVi to SWVf (SWVrat) was calculated. AR, SWVi, SWVb, and SWVrat were significantly larger in malignant lesions (all P < 0.001). A cutoff AR of 1.17 yielded the highest area under the receiver operating characteristic curveamong the various parameters (91.2% sensitivity, 85.9% specificity, 88.4% accuracy) for the differential diagnosis of small breast lesions, but this value did not significantly differ from SWVi (P = 0.1144). This AR cutoff indowngradingcategory 4a to category 3 would avoid 83.3% unnecessary biopsies, and improved diagnostic specificity up to 73.4% without decreasing sensitivity. AR and SWVi are efficient parameters for the differential diagnosis of small breast lesions, whichwill improve diagnostic specificity and reduce unnecessary biopsies.Si-Da WangLei WangZhi-Xian LiKang-Lai WeiXin-Hong LiaoYuan-Yuan ChenXue HuangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Si-Da Wang Lei Wang Zhi-Xian Li Kang-Lai Wei Xin-Hong Liao Yuan-Yuan Chen Xue Huang Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
description	Abstract To evaluate acoustic radiation force impulse (ARFI) inthe differential diagnosis of small (≤20 mm) solid breast lesions and identify the most efficient ARFI parameters. Conventional ultrasonography and ARFIwere performed in 120 patients with 121 small solid breast lesions. The area ratios (ARs) of the lesion on virtual touch tissue compared to B-mode were calculated. The shear wave velocity of the inner (SWVi) and boundary (SWVb) of the lesions and surrounding fatty tissue (SWVf) was measured. The ratio of SWVi to SWVf (SWVrat) was calculated. AR, SWVi, SWVb, and SWVrat were significantly larger in malignant lesions (all P < 0.001). A cutoff AR of 1.17 yielded the highest area under the receiver operating characteristic curveamong the various parameters (91.2% sensitivity, 85.9% specificity, 88.4% accuracy) for the differential diagnosis of small breast lesions, but this value did not significantly differ from SWVi (P = 0.1144). This AR cutoff indowngradingcategory 4a to category 3 would avoid 83.3% unnecessary biopsies, and improved diagnostic specificity up to 73.4% without decreasing sensitivity. AR and SWVi are efficient parameters for the differential diagnosis of small breast lesions, whichwill improve diagnostic specificity and reduce unnecessary biopsies.
format	article
author	Si-Da Wang Lei Wang Zhi-Xian Li Kang-Lai Wei Xin-Hong Liao Yuan-Yuan Chen Xue Huang
author_facet	Si-Da Wang Lei Wang Zhi-Xian Li Kang-Lai Wei Xin-Hong Liao Yuan-Yuan Chen Xue Huang
author_sort	Si-Da Wang
title	Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
title_short	Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
title_full	Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
title_fullStr	Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
title_full_unstemmed	Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?
title_sort	differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: is it valuable?
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/eafc4105395940279dbb8301a426786b
work_keys_str_mv	AT sidawang differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT leiwang differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT zhixianli differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT kanglaiwei differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT xinhongliao differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT yuanyuanchen differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable AT xuehuang differentialdiagnosticperformanceofacousticradiationforceimpulseimaginginsmall20mmbreastcancersisitvaluable
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Differential diagnostic performance of acoustic radiation force impulse imaging in small (≤20 mm) breast cancers: Is it valuable?

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