Repetition suppression to objects is modulated by stimulus-specific expectations

Abstract Repeated exposure to the same stimulus results in an attenuated brain response in cortical regions that are activated during the processing of that stimulus. This phenomenon, called repetition suppression (RS), has been shown to be modulated by expectation. Typically, this is achieved by va...

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Autores principales:	Christian Utzerath, Elexa St. John-Saaltink, Jan Buitelaar, Floris P. de Lange
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/eaff063fd9224105b1767ceb330dfbf2
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id	oai:doaj.org-article:eaff063fd9224105b1767ceb330dfbf2
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spelling	oai:doaj.org-article:eaff063fd9224105b1767ceb330dfbf22021-12-02T15:05:12ZRepetition suppression to objects is modulated by stimulus-specific expectations10.1038/s41598-017-09374-z2045-2322https://doaj.org/article/eaff063fd9224105b1767ceb330dfbf22017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-09374-zhttps://doaj.org/toc/2045-2322Abstract Repeated exposure to the same stimulus results in an attenuated brain response in cortical regions that are activated during the processing of that stimulus. This phenomenon, called repetition suppression (RS), has been shown to be modulated by expectation. Typically, this is achieved by varying the probability of stimulus repetitions (Prep) between blocks of an experiment, generating an abstract expectation that ‘things will repeat’. Here, we examined whether stimulus-specific expectations also modulate RS. We designed a task where expectation and repetition are manipulated independently, using stimulus-specific expectations. We investigated to which extent such stimulus-specific expectations modulated the visual evoked response to objects in lateral occipital cortex (LOC) and primary visual cortex (V1), using functional magnetic resonance imaging (fMRI). In LOC, we found that RS interacted with expectation, such that repetition suppression was more pronounced for unexpected relative to expected stimuli. Additionally, we found that the response of stimulus-preferring voxels in V1 was generally decreased when stimuli were expected. These results suggest that stimulus-specific expectations about objects modulate LOC and propagate back to the earliest cortical station processing visual input.Christian UtzerathElexa St. John-SaaltinkJan BuitelaarFloris P. de LangeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Christian Utzerath Elexa St. John-Saaltink Jan Buitelaar Floris P. de Lange Repetition suppression to objects is modulated by stimulus-specific expectations
description	Abstract Repeated exposure to the same stimulus results in an attenuated brain response in cortical regions that are activated during the processing of that stimulus. This phenomenon, called repetition suppression (RS), has been shown to be modulated by expectation. Typically, this is achieved by varying the probability of stimulus repetitions (Prep) between blocks of an experiment, generating an abstract expectation that ‘things will repeat’. Here, we examined whether stimulus-specific expectations also modulate RS. We designed a task where expectation and repetition are manipulated independently, using stimulus-specific expectations. We investigated to which extent such stimulus-specific expectations modulated the visual evoked response to objects in lateral occipital cortex (LOC) and primary visual cortex (V1), using functional magnetic resonance imaging (fMRI). In LOC, we found that RS interacted with expectation, such that repetition suppression was more pronounced for unexpected relative to expected stimuli. Additionally, we found that the response of stimulus-preferring voxels in V1 was generally decreased when stimuli were expected. These results suggest that stimulus-specific expectations about objects modulate LOC and propagate back to the earliest cortical station processing visual input.
format	article
author	Christian Utzerath Elexa St. John-Saaltink Jan Buitelaar Floris P. de Lange
author_facet	Christian Utzerath Elexa St. John-Saaltink Jan Buitelaar Floris P. de Lange
author_sort	Christian Utzerath
title	Repetition suppression to objects is modulated by stimulus-specific expectations
title_short	Repetition suppression to objects is modulated by stimulus-specific expectations
title_full	Repetition suppression to objects is modulated by stimulus-specific expectations
title_fullStr	Repetition suppression to objects is modulated by stimulus-specific expectations
title_full_unstemmed	Repetition suppression to objects is modulated by stimulus-specific expectations
title_sort	repetition suppression to objects is modulated by stimulus-specific expectations
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/eaff063fd9224105b1767ceb330dfbf2
work_keys_str_mv	AT christianutzerath repetitionsuppressiontoobjectsismodulatedbystimulusspecificexpectations AT elexastjohnsaaltink repetitionsuppressiontoobjectsismodulatedbystimulusspecificexpectations AT janbuitelaar repetitionsuppressiontoobjectsismodulatedbystimulusspecificexpectations AT florispdelange repetitionsuppressiontoobjectsismodulatedbystimulusspecificexpectations
_version_	1718388929148747776

Repetition suppression to objects is modulated by stimulus-specific expectations

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