Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

Plasma levels of neurological proteins have the potential to serve as biomarkers for neurological conditions. Here, Hillary et al. perform genome- and epigenome-wide association studies for 92 neurological proteins and identify 41 genomic loci for 33 proteins and 26 CpG sites for 9 proteins.

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Autores principales:	Robert F. Hillary, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Anne Seeboth, Qian Zhang, David C. Liewald, Kathryn L. Evans, Craig W. Ritchie, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary, Riccardo E. Marioni
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb036a77eede4ca581fe18fef0869311
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spelling	oai:doaj.org-article:eb036a77eede4ca581fe18fef08693112021-12-02T14:39:35ZGenome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 193610.1038/s41467-019-11177-x2041-1723https://doaj.org/article/eb036a77eede4ca581fe18fef08693112019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11177-xhttps://doaj.org/toc/2041-1723Plasma levels of neurological proteins have the potential to serve as biomarkers for neurological conditions. Here, Hillary et al. perform genome- and epigenome-wide association studies for 92 neurological proteins and identify 41 genomic loci for 33 proteins and 26 CpG sites for 9 proteins.Robert F. HillaryDaniel L. McCartneySarah E. HarrisAnna J. StevensonAnne SeebothQian ZhangDavid C. LiewaldKathryn L. EvansCraig W. RitchieElliot M. Tucker-DrobNaomi R. WrayAllan F. McRaePeter M. VisscherIan J. DearyRiccardo E. MarioniNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert F. Hillary Daniel L. McCartney Sarah E. Harris Anna J. Stevenson Anne Seeboth Qian Zhang David C. Liewald Kathryn L. Evans Craig W. Ritchie Elliot M. Tucker-Drob Naomi R. Wray Allan F. McRae Peter M. Visscher Ian J. Deary Riccardo E. Marioni Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
description	Plasma levels of neurological proteins have the potential to serve as biomarkers for neurological conditions. Here, Hillary et al. perform genome- and epigenome-wide association studies for 92 neurological proteins and identify 41 genomic loci for 33 proteins and 26 CpG sites for 9 proteins.
format	article
author	Robert F. Hillary Daniel L. McCartney Sarah E. Harris Anna J. Stevenson Anne Seeboth Qian Zhang David C. Liewald Kathryn L. Evans Craig W. Ritchie Elliot M. Tucker-Drob Naomi R. Wray Allan F. McRae Peter M. Visscher Ian J. Deary Riccardo E. Marioni
author_facet	Robert F. Hillary Daniel L. McCartney Sarah E. Harris Anna J. Stevenson Anne Seeboth Qian Zhang David C. Liewald Kathryn L. Evans Craig W. Ritchie Elliot M. Tucker-Drob Naomi R. Wray Allan F. McRae Peter M. Visscher Ian J. Deary Riccardo E. Marioni
author_sort	Robert F. Hillary
title	Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
title_short	Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
title_full	Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
title_fullStr	Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
title_full_unstemmed	Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936
title_sort	genome and epigenome wide studies of neurological protein biomarkers in the lothian birth cohort 1936
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/eb036a77eede4ca581fe18fef0869311
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Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

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