Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance
Very high risk neuroblastoma is characterised by increased MAPK signalling, and targeting MAPK signalling is a promising therapeutic strategy. We used a deeply characterised panel of neuroblastoma cell lines and found that the sensitivity to MEK inhibitors varied drastically between these cell lines...
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Autores principales: | , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/eb0d4b5da0ad4179bece23442265192b |
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