Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance
Very high risk neuroblastoma is characterised by increased MAPK signalling, and targeting MAPK signalling is a promising therapeutic strategy. We used a deeply characterised panel of neuroblastoma cell lines and found that the sensitivity to MEK inhibitors varied drastically between these cell lines...
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| Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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| Acceso en línea: | https://doaj.org/article/eb0d4b5da0ad4179bece23442265192b |
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Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
por Mathurin Dorel, Bertram Klinger, Tommaso Mari, Joern Toedling, Eric Blanc, Clemens Messerschmidt, Michal Nadler-Holly, Matthias Ziehm, Anja Sieber, Falk Hertwig, Dieter Beule, Angelika Eggert, Johannes H Schulte, Matthias Selbach, Nils Blüthgen
Publicado 2021
Enlace del recursoPublicado 2021
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