Identification of HIV transmitting CD11c+ human epidermal dendritic cells

Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HI...

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Autores principales:	Kirstie M. Bertram, Rachel A. Botting, Heeva Baharlou, Jake W. Rhodes, Hafsa Rana, J. Dinny Graham, Ellis Patrick, James Fletcher, Toby M. Plasto, Naomi R. Truong, Caroline Royle, Chloe M. Doyle, Orion Tong, Najla Nasr, Laith Barnouti, Mark P. Kohout, Andrew J. Brooks, Michael P. Wines, Peter Haertsch, Jake Lim, Martijn P. Gosselink, Grahame Ctercteko, Jacob D. Estes, Melissa J. Churchill, Paul U. Cameron, Eric Hunter, Muzlifah A. Haniffa, Anthony L. Cunningham, Andrew N. Harman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb12f23a92dd489b8e91e926a319cbf1
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spelling	oai:doaj.org-article:eb12f23a92dd489b8e91e926a319cbf12021-12-02T16:57:50ZIdentification of HIV transmitting CD11c+ human epidermal dendritic cells10.1038/s41467-019-10697-w2041-1723https://doaj.org/article/eb12f23a92dd489b8e91e926a319cbf12019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10697-whttps://doaj.org/toc/2041-1723Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HIV infection and transmission.Kirstie M. BertramRachel A. BottingHeeva BaharlouJake W. RhodesHafsa RanaJ. Dinny GrahamEllis PatrickJames FletcherToby M. PlastoNaomi R. TruongCaroline RoyleChloe M. DoyleOrion TongNajla NasrLaith BarnoutiMark P. KohoutAndrew J. BrooksMichael P. WinesPeter HaertschJake LimMartijn P. GosselinkGrahame CterctekoJacob D. EstesMelissa J. ChurchillPaul U. CameronEric HunterMuzlifah A. HaniffaAnthony L. CunninghamAndrew N. HarmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman Identification of HIV transmitting CD11c+ human epidermal dendritic cells
description	Composition and function of immune populations at barrier surfaces is crucial for response to infection. Here, the authors identify a population of dendritic cells in human epidermis, abundant in anogenital epithelia and distinct from Langerhans cells by surface phenotype and by high capacity for HIV infection and transmission.
format	article
author	Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman
author_facet	Kirstie M. Bertram Rachel A. Botting Heeva Baharlou Jake W. Rhodes Hafsa Rana J. Dinny Graham Ellis Patrick James Fletcher Toby M. Plasto Naomi R. Truong Caroline Royle Chloe M. Doyle Orion Tong Najla Nasr Laith Barnouti Mark P. Kohout Andrew J. Brooks Michael P. Wines Peter Haertsch Jake Lim Martijn P. Gosselink Grahame Ctercteko Jacob D. Estes Melissa J. Churchill Paul U. Cameron Eric Hunter Muzlifah A. Haniffa Anthony L. Cunningham Andrew N. Harman
author_sort	Kirstie M. Bertram
title	Identification of HIV transmitting CD11c+ human epidermal dendritic cells
title_short	Identification of HIV transmitting CD11c+ human epidermal dendritic cells
title_full	Identification of HIV transmitting CD11c+ human epidermal dendritic cells
title_fullStr	Identification of HIV transmitting CD11c+ human epidermal dendritic cells
title_full_unstemmed	Identification of HIV transmitting CD11c+ human epidermal dendritic cells
title_sort	identification of hiv transmitting cd11c+ human epidermal dendritic cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/eb12f23a92dd489b8e91e926a319cbf1
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Identification of HIV transmitting CD11c+ human epidermal dendritic cells

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