Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
Daniel Y Bigman, Bradford D Bobrin Department of Psychiatry, Cooper University Hospital, Cooper Medical School of Rowan University, Camden, NJ, USA Abstract: Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von E...
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Dove Medical Press
2018
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oai:doaj.org-article:eb17703547f640fb9dd5185ad190611f2021-12-02T02:17:14ZVon Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa1178-2021https://doaj.org/article/eb17703547f640fb9dd5185ad190611f2018-04-01T00:00:00Zhttps://www.dovepress.com/von-economos-disease-and-postencephalitic-parkinsonism-responsive-to-c-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Daniel Y Bigman, Bradford D Bobrin Department of Psychiatry, Cooper University Hospital, Cooper Medical School of Rowan University, Camden, NJ, USA Abstract: Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von Economo’s disease [EL]), with PEP developing immediately after the acute phase of EL or at some time later. EL was classically described by von Economo and has somnolent-ophthalmoplegic, hyperkinetic, and amyostatic-akinetic forms. Previous cases have reported success with levodopa in PEP. We report a case with PEP showing success after administration of levodopa and carbidopa. This case would support the hypothesis that this syndrome effects dopamine neurotransmission. Keywords: von Economo, encephalitis lethargica, postencephalitic parkinsonism, carbidopa, levodopa, catatoniaBigman DYBobrin BDDove Medical Pressarticlevon Economoencephalitis lethargicaPostencephalitis ParkinsonismcarbidopalevodopacatatoniaNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 927-931 (2018) |
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von Economo encephalitis lethargica Postencephalitis Parkinsonism carbidopa levodopa catatonia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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von Economo encephalitis lethargica Postencephalitis Parkinsonism carbidopa levodopa catatonia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Bigman DY Bobrin BD Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
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Daniel Y Bigman, Bradford D Bobrin Department of Psychiatry, Cooper University Hospital, Cooper Medical School of Rowan University, Camden, NJ, USA Abstract: Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von Economo’s disease [EL]), with PEP developing immediately after the acute phase of EL or at some time later. EL was classically described by von Economo and has somnolent-ophthalmoplegic, hyperkinetic, and amyostatic-akinetic forms. Previous cases have reported success with levodopa in PEP. We report a case with PEP showing success after administration of levodopa and carbidopa. This case would support the hypothesis that this syndrome effects dopamine neurotransmission. Keywords: von Economo, encephalitis lethargica, postencephalitic parkinsonism, carbidopa, levodopa, catatonia |
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article |
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Bigman DY Bobrin BD |
author_facet |
Bigman DY Bobrin BD |
author_sort |
Bigman DY |
title |
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
title_short |
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
title_full |
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
title_fullStr |
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
title_full_unstemmed |
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
title_sort |
von economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa |
publisher |
Dove Medical Press |
publishDate |
2018 |
url |
https://doaj.org/article/eb17703547f640fb9dd5185ad190611f |
work_keys_str_mv |
AT bigmandy voneconomorsquosdiseaseandpostencephaliticparkinsonismresponsivetocarbidopaandlevodopa AT bobrinbd voneconomorsquosdiseaseandpostencephaliticparkinsonismresponsivetocarbidopaandlevodopa |
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1718402627778117632 |