Induction of HIF-1α by HIV-1 Infection in CD4<sup>+</sup> T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation
ABSTRACT Chronic immune activation and inflammation are hallmarks of HIV-1 infection and a major cause of serious non-AIDS events in HIV-1-infected individuals on antiretroviral treatment (ART). Herein, we show that cytosolic double-stranded DNA (dsDNA) generated in infected CD4+ T cells during the...
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| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/eb1accfedd334fa5b0ed56cc2700e7cd |
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