Activation of ERAD pathway by human hepatitis B virus modulates viral and subviral particle production.
Hepatitis B virus (HBV) belongs to the Hepadnaviridae family of enveloped DNA viruses. It was previously shown that HBV can induce endoplasmic reticulum (ER) stress and activate the IRE1-XBP1 pathway of the unfolded protein response (UPR), through the expression of the viral regulatory protein X (HB...
Guardado en:
Autores principales: | Catalin Lazar, Alina Macovei, Stefana Petrescu, Norica Branza-Nichita |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/eb1f9ce9004744e6b3898e8de911feb6 |
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