DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1

SWI/SNF genes are commonly found to be mutated in different cancers. Here the authors report that the remodelers BRM and BRG1 are necessary for efficient nucleotide excision repair by promoting the expression of TFIIH subunit GTF2H1.

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Autores principales:	Cristina Ribeiro-Silva, Özge Z. Aydin, Raquel Mesquita-Ribeiro, Jana Slyskova, Angela Helfricht, Jurgen A. Marteijn, Jan H. J. Hoeijmakers, Hannes Lans, Wim Vermeulen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb220f4c08794f88ad5354ea35208f77
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spelling	oai:doaj.org-article:eb220f4c08794f88ad5354ea35208f772021-12-02T17:32:18ZDNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H110.1038/s41467-018-06402-y2041-1723https://doaj.org/article/eb220f4c08794f88ad5354ea35208f772018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06402-yhttps://doaj.org/toc/2041-1723SWI/SNF genes are commonly found to be mutated in different cancers. Here the authors report that the remodelers BRM and BRG1 are necessary for efficient nucleotide excision repair by promoting the expression of TFIIH subunit GTF2H1.Cristina Ribeiro-SilvaÖzge Z. AydinRaquel Mesquita-RibeiroJana SlyskovaAngela HelfrichtJurgen A. MarteijnJan H. J. HoeijmakersHannes LansWim VermeulenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cristina Ribeiro-Silva Özge Z. Aydin Raquel Mesquita-Ribeiro Jana Slyskova Angela Helfricht Jurgen A. Marteijn Jan H. J. Hoeijmakers Hannes Lans Wim Vermeulen DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
description	SWI/SNF genes are commonly found to be mutated in different cancers. Here the authors report that the remodelers BRM and BRG1 are necessary for efficient nucleotide excision repair by promoting the expression of TFIIH subunit GTF2H1.
format	article
author	Cristina Ribeiro-Silva Özge Z. Aydin Raquel Mesquita-Ribeiro Jana Slyskova Angela Helfricht Jurgen A. Marteijn Jan H. J. Hoeijmakers Hannes Lans Wim Vermeulen
author_facet	Cristina Ribeiro-Silva Özge Z. Aydin Raquel Mesquita-Ribeiro Jana Slyskova Angela Helfricht Jurgen A. Marteijn Jan H. J. Hoeijmakers Hannes Lans Wim Vermeulen
author_sort	Cristina Ribeiro-Silva
title	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
title_short	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
title_full	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
title_fullStr	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
title_full_unstemmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1
title_sort	dna damage sensitivity of swi/snf-deficient cells depends on tfiih subunit p62/gtf2h1
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/eb220f4c08794f88ad5354ea35208f77
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DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1

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