Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key man...
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Nature Portfolio
2021
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oai:doaj.org-article:eb25c5882deb4c9a8bdcaa77f44d63b72021-12-02T14:53:37ZTurn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope10.1038/s41467-021-24602-x2041-1723https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b72021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24602-xhttps://doaj.org/toc/2041-1723The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key manner.Aaron BlanchardJ. Dale CombsJoshua M. BrockmanAnna V. KellnerRoxanne GlazierHanquan SuRachel L. BenderAlisina S. BazrafshanWenchun ChenM. Edward QuachRenhao LiAlexa L. MattheysesKhalid SalaitaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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Science Q |
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Science Q Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
description |
The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key manner. |
format |
article |
author |
Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita |
author_facet |
Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita |
author_sort |
Aaron Blanchard |
title |
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
title_short |
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
title_full |
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
title_fullStr |
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
title_full_unstemmed |
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
title_sort |
turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b7 |
work_keys_str_mv |
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