Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope

The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key man...

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Main Authors:	Aaron Blanchard, J. Dale Combs, Joshua M. Brockman, Anna V. Kellner, Roxanne Glazier, Hanquan Su, Rachel L. Bender, Alisina S. Bazrafshan, Wenchun Chen, M. Edward Quach, Renhao Li, Alexa L. Mattheyses, Khalid Salaita
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b7
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spelling	oai:doaj.org-article:eb25c5882deb4c9a8bdcaa77f44d63b72021-12-02T14:53:37ZTurn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope10.1038/s41467-021-24602-x2041-1723https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b72021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24602-xhttps://doaj.org/toc/2041-1723The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key manner.Aaron BlanchardJ. Dale CombsJoshua M. BrockmanAnna V. KellnerRoxanne GlazierHanquan SuRachel L. BenderAlisina S. BazrafshanWenchun ChenM. Edward QuachRenhao LiAlexa L. MattheysesKhalid SalaitaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
description	The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence polarisation, can be used for MFM in a turn-key manner.
format	article
author	Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita
author_facet	Aaron Blanchard J. Dale Combs Joshua M. Brockman Anna V. Kellner Roxanne Glazier Hanquan Su Rachel L. Bender Alisina S. Bazrafshan Wenchun Chen M. Edward Quach Renhao Li Alexa L. Mattheyses Khalid Salaita
author_sort	Aaron Blanchard
title	Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
title_short	Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
title_full	Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
title_fullStr	Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
title_full_unstemmed	Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
title_sort	turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b7
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Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope

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