Long-term optical brain imaging in live adult fruit flies

Time-lapse imaging studies of more than a day in the fly brain have been infeasible until now. Here the authors present a laser microsurgery approach to create a permanent window in the fly cuticle to enable time-lapse imaging of neural architecture and dynamics for up to 10–50 days.

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Autores principales:	Cheng Huang, Jessica R. Maxey, Supriyo Sinha, Joan Savall, Yiyang Gong, Mark J. Schnitzer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb2d1b6d6bab44e19661338f459d5e9d
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spelling	oai:doaj.org-article:eb2d1b6d6bab44e19661338f459d5e9d2021-12-02T15:34:19ZLong-term optical brain imaging in live adult fruit flies10.1038/s41467-018-02873-12041-1723https://doaj.org/article/eb2d1b6d6bab44e19661338f459d5e9d2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02873-1https://doaj.org/toc/2041-1723Time-lapse imaging studies of more than a day in the fly brain have been infeasible until now. Here the authors present a laser microsurgery approach to create a permanent window in the fly cuticle to enable time-lapse imaging of neural architecture and dynamics for up to 10–50 days.Cheng HuangJessica R. MaxeySupriyo SinhaJoan SavallYiyang GongMark J. SchnitzerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cheng Huang Jessica R. Maxey Supriyo Sinha Joan Savall Yiyang Gong Mark J. Schnitzer Long-term optical brain imaging in live adult fruit flies
description	Time-lapse imaging studies of more than a day in the fly brain have been infeasible until now. Here the authors present a laser microsurgery approach to create a permanent window in the fly cuticle to enable time-lapse imaging of neural architecture and dynamics for up to 10–50 days.
format	article
author	Cheng Huang Jessica R. Maxey Supriyo Sinha Joan Savall Yiyang Gong Mark J. Schnitzer
author_facet	Cheng Huang Jessica R. Maxey Supriyo Sinha Joan Savall Yiyang Gong Mark J. Schnitzer
author_sort	Cheng Huang
title	Long-term optical brain imaging in live adult fruit flies
title_short	Long-term optical brain imaging in live adult fruit flies
title_full	Long-term optical brain imaging in live adult fruit flies
title_fullStr	Long-term optical brain imaging in live adult fruit flies
title_full_unstemmed	Long-term optical brain imaging in live adult fruit flies
title_sort	long-term optical brain imaging in live adult fruit flies
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/eb2d1b6d6bab44e19661338f459d5e9d
work_keys_str_mv	AT chenghuang longtermopticalbrainimaginginliveadultfruitflies AT jessicarmaxey longtermopticalbrainimaginginliveadultfruitflies AT supriyosinha longtermopticalbrainimaginginliveadultfruitflies AT joansavall longtermopticalbrainimaginginliveadultfruitflies AT yiyanggong longtermopticalbrainimaginginliveadultfruitflies AT markjschnitzer longtermopticalbrainimaginginliveadultfruitflies
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Long-term optical brain imaging in live adult fruit flies

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