Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways

Mitochondria can undergo shape changes as a result of fusion and fission events. Here the authors describe how insulin signalling regulates mitochondrial fusion in C. elegans, and show that mitochondrial fusion is necessary, but not sufficient, for longevity of worms with mutations that increase lif...

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Autores principales:	Snehal N. Chaudhari, Edward T. Kipreos
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb3d10986971495c9e8d4a385fe441a1
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spelling	oai:doaj.org-article:eb3d10986971495c9e8d4a385fe441a12021-12-02T10:47:59ZIncreased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways10.1038/s41467-017-00274-42041-1723https://doaj.org/article/eb3d10986971495c9e8d4a385fe441a12017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00274-4https://doaj.org/toc/2041-1723Mitochondria can undergo shape changes as a result of fusion and fission events. Here the authors describe how insulin signalling regulates mitochondrial fusion in C. elegans, and show that mitochondrial fusion is necessary, but not sufficient, for longevity of worms with mutations that increase lifespan.Snehal N. ChaudhariEdward T. KipreosNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Snehal N. Chaudhari Edward T. Kipreos Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
description	Mitochondria can undergo shape changes as a result of fusion and fission events. Here the authors describe how insulin signalling regulates mitochondrial fusion in C. elegans, and show that mitochondrial fusion is necessary, but not sufficient, for longevity of worms with mutations that increase lifespan.
format	article
author	Snehal N. Chaudhari Edward T. Kipreos
author_facet	Snehal N. Chaudhari Edward T. Kipreos
author_sort	Snehal N. Chaudhari
title	Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
title_short	Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
title_full	Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
title_fullStr	Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
title_full_unstemmed	Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
title_sort	increased mitochondrial fusion allows the survival of older animals in diverse c. elegans longevity pathways
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/eb3d10986971495c9e8d4a385fe441a1
work_keys_str_mv	AT snehalnchaudhari increasedmitochondrialfusionallowsthesurvivalofolderanimalsindiverseceleganslongevitypathways AT edwardtkipreos increasedmitochondrialfusionallowsthesurvivalofolderanimalsindiverseceleganslongevitypathways
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Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways

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