Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ

MS2 is a single-stranded RNA bacteriophage that infects its host via adsorption to bacterial pili. Here the authors visualize the MS2 virion with asymmetric cryo-EM reconstruction, revealing that the genome of MS2 adopts a specific structure of asymmetrically distributed stem-loops connected to the...

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Autores principales:	Roman I Koning, Josue Gomez-Blanco, Inara Akopjana, Javier Vargas, Andris Kazaks, Kaspars Tars, José María Carazo, Abraham J. Koster
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb4699af3d054381a83bc6accac7f614
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spelling	oai:doaj.org-article:eb4699af3d054381a83bc6accac7f6142021-12-02T17:32:21ZAsymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ10.1038/ncomms125242041-1723https://doaj.org/article/eb4699af3d054381a83bc6accac7f6142016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12524https://doaj.org/toc/2041-1723MS2 is a single-stranded RNA bacteriophage that infects its host via adsorption to bacterial pili. Here the authors visualize the MS2 virion with asymmetric cryo-EM reconstruction, revealing that the genome of MS2 adopts a specific structure of asymmetrically distributed stem-loops connected to the capsid.Roman I KoningJosue Gomez-BlancoInara AkopjanaJavier VargasAndris KazaksKaspars TarsJosé María CarazoAbraham J. KosterNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Roman I Koning Josue Gomez-Blanco Inara Akopjana Javier Vargas Andris Kazaks Kaspars Tars José María Carazo Abraham J. Koster Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
description	MS2 is a single-stranded RNA bacteriophage that infects its host via adsorption to bacterial pili. Here the authors visualize the MS2 virion with asymmetric cryo-EM reconstruction, revealing that the genome of MS2 adopts a specific structure of asymmetrically distributed stem-loops connected to the capsid.
format	article
author	Roman I Koning Josue Gomez-Blanco Inara Akopjana Javier Vargas Andris Kazaks Kaspars Tars José María Carazo Abraham J. Koster
author_facet	Roman I Koning Josue Gomez-Blanco Inara Akopjana Javier Vargas Andris Kazaks Kaspars Tars José María Carazo Abraham J. Koster
author_sort	Roman I Koning
title	Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
title_short	Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
title_full	Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
title_fullStr	Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
title_full_unstemmed	Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
title_sort	asymmetric cryo-em reconstruction of phage ms2 reveals genome structure in situ
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/eb4699af3d054381a83bc6accac7f614
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Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ

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