Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing

ABSTRACT Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct therapy for Ebola virus disease (EVD) dur...

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Auteurs principaux: Punya Shrivastava-Ranjan, Mike Flint, Éric Bergeron, Anita K. McElroy, Payel Chatterjee, César G. Albariño, Stuart T. Nichol, Christina F. Spiropoulou
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
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Accès en ligne:https://doaj.org/article/eb5a3a1b6f3145578abdd9b3d291c4b9
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