Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases

Bacteria-targeting nanomaterials have been widely used in the diagnosis and treatment of bacterial infectious diseases. These nanomaterials show great potential as antimicrobial agents due to their broad-spectrum antibacterial capacity and relatively low toxicity. Recently, nanomaterials have improv...

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Autores principales:	Yuan-Pin Hung, Yu-Fon Chen, Pei-Jane Tsai, I-Hsiu Huang, Wen-Chien Ko, Jeng-Shiung Jan
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	nanoparticle silver nanoparticle biofilms implants bacterial infection polymers Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/eb5cc3982b814c1f945e8b6da8ac10c5
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id	oai:doaj.org-article:eb5cc3982b814c1f945e8b6da8ac10c5
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spelling	oai:doaj.org-article:eb5cc3982b814c1f945e8b6da8ac10c52021-11-25T18:41:45ZAdvances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases10.3390/pharmaceutics131119131999-4923https://doaj.org/article/eb5cc3982b814c1f945e8b6da8ac10c52021-11-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1913https://doaj.org/toc/1999-4923Bacteria-targeting nanomaterials have been widely used in the diagnosis and treatment of bacterial infectious diseases. These nanomaterials show great potential as antimicrobial agents due to their broad-spectrum antibacterial capacity and relatively low toxicity. Recently, nanomaterials have improved the accurate detection of pathogens, provided therapeutic strategies against nosocomial infections and facilitated the delivery of antigenic protein vaccines that induce humoral and cellular immunity. Biomaterial implants, which have traditionally been hindered by bacterial colonization, benefit from their ability to prevent bacteria from forming biofilms and spreading into adjacent tissues. Wound repair is improving in terms of both the function and prevention of bacterial infection, as we tailor nanomaterials to their needs, select encapsulation methods and materials, incorporate activation systems and add immune-activating adjuvants. Recent years have produced numerous advances in their antibacterial applications, but even further expansion in the diagnosis and treatment of infectious diseases is expected in the future.Yuan-Pin HungYu-Fon ChenPei-Jane TsaiI-Hsiu HuangWen-Chien KoJeng-Shiung JanMDPI AGarticlenanoparticlesilver nanoparticlebiofilmsimplantsbacterial infectionpolymersPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1913, p 1913 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanoparticle silver nanoparticle biofilms implants bacterial infection polymers Pharmacy and materia medica RS1-441
spellingShingle	nanoparticle silver nanoparticle biofilms implants bacterial infection polymers Pharmacy and materia medica RS1-441 Yuan-Pin Hung Yu-Fon Chen Pei-Jane Tsai I-Hsiu Huang Wen-Chien Ko Jeng-Shiung Jan Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
description	Bacteria-targeting nanomaterials have been widely used in the diagnosis and treatment of bacterial infectious diseases. These nanomaterials show great potential as antimicrobial agents due to their broad-spectrum antibacterial capacity and relatively low toxicity. Recently, nanomaterials have improved the accurate detection of pathogens, provided therapeutic strategies against nosocomial infections and facilitated the delivery of antigenic protein vaccines that induce humoral and cellular immunity. Biomaterial implants, which have traditionally been hindered by bacterial colonization, benefit from their ability to prevent bacteria from forming biofilms and spreading into adjacent tissues. Wound repair is improving in terms of both the function and prevention of bacterial infection, as we tailor nanomaterials to their needs, select encapsulation methods and materials, incorporate activation systems and add immune-activating adjuvants. Recent years have produced numerous advances in their antibacterial applications, but even further expansion in the diagnosis and treatment of infectious diseases is expected in the future.
format	article
author	Yuan-Pin Hung Yu-Fon Chen Pei-Jane Tsai I-Hsiu Huang Wen-Chien Ko Jeng-Shiung Jan
author_facet	Yuan-Pin Hung Yu-Fon Chen Pei-Jane Tsai I-Hsiu Huang Wen-Chien Ko Jeng-Shiung Jan
author_sort	Yuan-Pin Hung
title	Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
title_short	Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
title_full	Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
title_fullStr	Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
title_full_unstemmed	Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases
title_sort	advances in the application of nanomaterials as treatments for bacterial infectious diseases
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/eb5cc3982b814c1f945e8b6da8ac10c5
work_keys_str_mv	AT yuanpinhung advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases AT yufonchen advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases AT peijanetsai advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases AT ihsiuhuang advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases AT wenchienko advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases AT jengshiungjan advancesintheapplicationofnanomaterialsastreatmentsforbacterialinfectiousdiseases
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Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases

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