Synthetic hydrogel nanoparticles for sepsis therapy

Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, and demonstrate sepsis treatment in a murine model.

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Detalles Bibliográficos
Autores principales:	Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Ting-Hui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb612ef6ea67468793984170be09b6f2
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spelling	oai:doaj.org-article:eb612ef6ea67468793984170be09b6f22021-12-02T17:26:56ZSynthetic hydrogel nanoparticles for sepsis therapy10.1038/s41467-021-25847-22041-1723https://doaj.org/article/eb612ef6ea67468793984170be09b6f22021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25847-2https://doaj.org/toc/2041-1723Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, and demonstrate sepsis treatment in a murine model.Hiroyuki KoideAnna OkishimaYu HoshinoYuri KamonKeiichi YoshimatsuKazuhiro SaitoIkumi YamauchiSaki AriizumiYuqi ZhouTing-Hui XiaoKeisuke GodaNaoto OkuTomohiro AsaiKenneth J. SheaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hiroyuki Koide Anna Okishima Yu Hoshino Yuri Kamon Keiichi Yoshimatsu Kazuhiro Saito Ikumi Yamauchi Saki Ariizumi Yuqi Zhou Ting-Hui Xiao Keisuke Goda Naoto Oku Tomohiro Asai Kenneth J. Shea Synthetic hydrogel nanoparticles for sepsis therapy
description	Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, and demonstrate sepsis treatment in a murine model.
format	article
author	Hiroyuki Koide Anna Okishima Yu Hoshino Yuri Kamon Keiichi Yoshimatsu Kazuhiro Saito Ikumi Yamauchi Saki Ariizumi Yuqi Zhou Ting-Hui Xiao Keisuke Goda Naoto Oku Tomohiro Asai Kenneth J. Shea
author_facet	Hiroyuki Koide Anna Okishima Yu Hoshino Yuri Kamon Keiichi Yoshimatsu Kazuhiro Saito Ikumi Yamauchi Saki Ariizumi Yuqi Zhou Ting-Hui Xiao Keisuke Goda Naoto Oku Tomohiro Asai Kenneth J. Shea
author_sort	Hiroyuki Koide
title	Synthetic hydrogel nanoparticles for sepsis therapy
title_short	Synthetic hydrogel nanoparticles for sepsis therapy
title_full	Synthetic hydrogel nanoparticles for sepsis therapy
title_fullStr	Synthetic hydrogel nanoparticles for sepsis therapy
title_full_unstemmed	Synthetic hydrogel nanoparticles for sepsis therapy
title_sort	synthetic hydrogel nanoparticles for sepsis therapy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eb612ef6ea67468793984170be09b6f2
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Synthetic hydrogel nanoparticles for sepsis therapy

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