Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded β-Glucan Particles

ABSTRACT β-Glucan particles (GPs) are purified Saccharomyces cerevisiae cell walls treated so that they are primarily β1,3-d-glucans and free of mannans and proteins. GPs are phagocytosed by dendritic cells (DCs) via the Dectin-1 receptor, and this interaction stimulates proinflammatory cytokine sec...

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Autores principales: Haibin Huang, Gary R. Ostroff, Chrono K. Lee, Charles A. Specht, Stuart M. Levitz
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2010
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Acceso en línea:https://doaj.org/article/eb6a58b5a92b4ef39f3c7b867e109268
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