RAB10: an Alzheimer’s disease resilience locus and potential drug target

Código QR

RAB10: an Alzheimer’s disease resilience locus and potential drug target

Justina P Tavana,1,* Matthew Rosene,2,* Nick O Jensen,2 Perry G Ridge,1 John SK Kauwe,1,3 Celeste M Karch2,4 1Department of Biology, Brigham Young University, Provo, UT 84602, USA; 2Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA; 3Department of Neuroscience, Brigham...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tavana JP, Rosene M, Jensen NO, Ridge PG, Kauwe JSK, Karch CM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Alzheimer disease RAB10 Retromer APP resilience GTPase Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/eb7048d406034231a0061c376e346c0a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Nectin stabilization at adherens junctions is counteracted by Rab5a-dependent endocytosis
por: Pasquale Cervero, et al.
Publicado: (2021)

Role of Rab GTPases in Hepatocellular Carcinoma
por: Yang CC, et al.
Publicado: (2021)

The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7
por: Evgeniya Trofimenko, et al.
Publicado: (2021)

Extracellular CIRP-Impaired Rab26 Restrains EPOR-Mediated Macrophage Polarization in Acute Lung Injury
por: Wen Zhang, et al.
Publicado: (2021)

A Role for the VPS Retromer in <italic toggle="yes">Brucella</italic> Intracellular Replication Revealed by Genomewide siRNA Screening
por: Alain Casanova, et al.
Publicado: (2019)

Focus on the Small GTPase Rab1: A Key Player in the Pathogenesis of Parkinson’s Disease
por: José Ángel Martínez-Menárguez, et al.
Publicado: (2021)

<italic toggle="yes">Yersinia pestis</italic> Targets the Host Endosome Recycling Pathway during the Biogenesis of the <italic toggle="yes">Yersinia</italic>-Containing Vacuole To Avoid Killing by Macrophages
por: Michael G. Connor, et al.
Publicado: (2018)

Relationship between Rab and insulin-like proteins in the nervous system of Bombyx mori
por: Tomohide UNO, et al.
Publicado: (2021)

A novel live-cell imaging assay reveals regulation of endosome maturation
por: Maria Podinovskaia, et al.
Publicado: (2021)

PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer’s disease: in vitro and in vivo studies
por: Silva-Abreu M, et al.
Publicado: (2018)

LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectives
por: Atashrazm F, et al.
Publicado: (2016)

Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the <italic toggle="yes">Brucella</italic> Intracellular Cycle
por: Erin P. Smith, et al.
Publicado: (2020)

RAB42 Promotes Glioma Pathogenesis via the VEGF Signaling Pathway
por: Baoling Liu, et al.
Publicado: (2021)

Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins
por: Maria Sol Herrera-Cruz, et al.
Publicado: (2021)

Rab11a Regulates the Development of Cilia and Establishment of Planar Cell Polarity in Mammalian Vestibular Hair Cells
por: Bin-Jun Chen, et al.
Publicado: (2021)

Circ_0013359 facilitates the tumorigenicity of melanoma by regulating miR-136-5p/RAB9A axis
por: Zhang Qi, et al.
Publicado: (2021)

Identification of Rab18 as an Essential Host Factor for BK Polyomavirus Infection Using a Whole-Genome RNA Interference Screen
por: Linbo Zhao, et al.
Publicado: (2017)

Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer
por: Dalu Wang, et al.
Publicado: (2021)

Who is important and who is not? On the reasons for including two distinguished renaissance Rab canons from the Stančić family into the integral alphabetical list of entries of the Croatian Biographical Dictionary
por: Meri Kunčić
Publicado: (2021)

MiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells
por: Panpan Xu, et al.
Publicado: (2020)

Genetic variants associated with neurodegenerative Alzheimer disease in natural models
por: Salazar,Claudia, et al.
Publicado: (2016)

Resiliency Analysis of Hybrid Energy Systems within Interconnected Infrastructures
por: Hossam A. Gabbar
Publicado: (2021)

Caracterización del lenguaje en las variantes lingüísticas de la Afasia Progresiva Primaria
por: Pérez Lancho,Mª Cruz, et al.
Publicado: (2020)

Rab18 binds to classical swine fever virus NS5A and mediates viral replication and assembly in swine umbilical vein endothelial cells
por: Liang Zhang, et al.
Publicado: (2020)

Deliver on Time or Pay the Fine: Scheduling in Membrane Trafficking
por: Giampaolo Placidi, et al.
Publicado: (2021)

A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling
por: Sho W Suzuki, et al.
Publicado: (2021)

Resilience in the Cyberworld: Definitions, Features and Models
por: Elisabeth Vogel, et al.
Publicado: (2021)

Proper Balance of Small GTPase <i>rab10</i> Is Critical for PGC Migration in Zebrafish
por: Chengyu Mo, et al.
Publicado: (2021)

Does resilience impact food waste? Moving the debate on
por: Flávio Henrique de Oliveira Costa, et al.
Publicado: (2021)

Targeting miR-185-3p Inhibits Head and Neck Squamous Cell Carcinoma by Modulating RAB25
por: Xueping Wang, et al.
Publicado: (2021)

Iron Homeostasis Disorder and Alzheimer’s Disease
por: Yu Peng, et al.
Publicado: (2021)

Developing an Interactive University Orientation App: Potential Users’ Feedback
por: Radzuwan Ab Rashid, et al.
Publicado: (2021)

Identification of a novel mutation in APP gene in a Thai subject with early-onset Alzheimer's disease
por: Giau VV, et al.
Publicado: (2018)

<named-content content-type="genus-species">Clostridium sordellii</named-content> Lethal-Toxin Autoprocessing and Membrane Localization Activities Drive GTPase Glucosylation Profiles in Endothelial Cells
por: Ryan Craven, et al.
Publicado: (2016)

Assessing the Social-ecological Resilience of Organic Farmers in Chiang Mai Province, Thailand
por: Chaiteera Panpakdee, et al.
Publicado: (2021)

Threaten me softly: A review of potential dating app risks
por: Anh Phan, et al.
Publicado: (2021)

Resilience: Lessons to be learned from safety and acceptable risk
por: Kosovac Anna, et al.
Publicado: (2021)

Resilience thinking and urban planning in a coastal environment at risks of tsunamis: the case study of Mehuín, Chile
por: Villagra,Paula, et al.
Publicado: (2016)

Pursuit of precision medicine: Systems biology approaches in Alzheimer's disease mouse models
por: Brianna Gurdon, et al.
Publicado: (2021)

EPEC Recruits a Cdc42-Specific GEF, Frabin, To Facilitate PAK Activation and Host Cell Colonization
por: Vikash Singh, et al.
Publicado: (2020)