Intrinsic basis of thermostability of prolyl oligopeptidase from Pyrococcus furiosus

Abstract Salt-bridges play a key role in the thermostability of proteins adapted in stress environments whose intrinsic basis remains to be understood. We find that the higher hydrophilicity of PfP than that of HuP is due to the charged but not the polar residues. The primary role of these residues...

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Autores principales: Sahini Banerjee, Parth Sarthi Sen Gupta, Rifat Nawaz Ul Islam, Amal Kumar Bandyopadhyay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/eb709fb6a7a34864b0ace9527010abca
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