Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice

GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.

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Autores principales:	Sangsu Bang, Christopher R. Donnelly, Xin Luo, Maria Toro-Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V. Bortsov, Emily R. Derbyshire, Ru-Rong Ji
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb825ea936f54c5198d6ef87a574a599
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spelling	oai:doaj.org-article:eb825ea936f54c5198d6ef87a574a5992021-12-02T11:39:37ZActivation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice10.1038/s41467-021-21940-82041-1723https://doaj.org/article/eb825ea936f54c5198d6ef87a574a5992021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21940-8https://doaj.org/toc/2041-1723GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.Sangsu BangChristopher R. DonnellyXin LuoMaria Toro-MorenoXueshu TaoZilong WangSharat ChandraAndrey V. BortsovEmily R. DerbyshireRu-Rong JiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sangsu Bang Christopher R. Donnelly Xin Luo Maria Toro-Moreno Xueshu Tao Zilong Wang Sharat Chandra Andrey V. Bortsov Emily R. Derbyshire Ru-Rong Ji Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
description	GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.
format	article
author	Sangsu Bang Christopher R. Donnelly Xin Luo Maria Toro-Moreno Xueshu Tao Zilong Wang Sharat Chandra Andrey V. Bortsov Emily R. Derbyshire Ru-Rong Ji
author_facet	Sangsu Bang Christopher R. Donnelly Xin Luo Maria Toro-Moreno Xueshu Tao Zilong Wang Sharat Chandra Andrey V. Bortsov Emily R. Derbyshire Ru-Rong Ji
author_sort	Sangsu Bang
title	Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
title_short	Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
title_full	Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
title_fullStr	Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
title_full_unstemmed	Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
title_sort	activation of gpr37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eb825ea936f54c5198d6ef87a574a599
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Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice

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