Strategies for early recognition of cutaneous melanoma—present and future

Cutaneous melanoma is a highly aggressive malignant tumor of skin melanocytes with an increasing incidence in most countries of the world, especially in the fair-skinned populations. Despite all preventive and therapeutic efforts, malignant melanoma is still the most lethal skin cancer. A delayed d...

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Autores principales:	Franziska Brehmer, Marina Ulrich, Holger A. Haenssle
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2012
Materias:	cutaneous melanoma melanoma risk factors early recognition dermoscopy confocal laser scanning microscopy Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/eb93bcb9616b4eb5b97bd8f870938f69
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spelling	oai:doaj.org-article:eb93bcb9616b4eb5b97bd8f870938f692021-11-17T08:33:05ZStrategies for early recognition of cutaneous melanoma—present and future10.5826/dpc.0203a062160-9381https://doaj.org/article/eb93bcb9616b4eb5b97bd8f870938f692012-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1179https://doaj.org/toc/2160-9381 Cutaneous melanoma is a highly aggressive malignant tumor of skin melanocytes with an increasing incidence in most countries of the world, especially in the fair-skinned populations. Despite all preventive and therapeutic efforts, malignant melanoma is still the most lethal skin cancer. A delayed diagnosis results in an advanced stage and worsened prognosis. Once distant metastases are present, the five-year survival rate is less than 10 percent. At the same time, patients may be cured by an early diagnosis of cutaneous melanoma followed by a wide excision. Therefore, the early detection of melanoma at curable stages is crucial for the patients’ survival. Besides the investigation of pigmented lesions with the unaided eye, a wide range of examination techniques for improved diagnostic accuracy have been developed and validated in clinical trials. However, none of these techniques are able to provide a definite and final diagnosis or to replace an excisional biopsy of suspicious lesions followed by histological analysis. This review provides a concise overview of general principles as well as current and future strategies for an improved early diagnosis of cutaneous melanoma. Franziska BrehmerMarina UlrichHolger A. HaenssleMattioli1885articlecutaneous melanomamelanoma risk factorsearly recognitiondermoscopyconfocal laser scanning microscopyDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	cutaneous melanoma melanoma risk factors early recognition dermoscopy confocal laser scanning microscopy Dermatology RL1-803
spellingShingle	cutaneous melanoma melanoma risk factors early recognition dermoscopy confocal laser scanning microscopy Dermatology RL1-803 Franziska Brehmer Marina Ulrich Holger A. Haenssle Strategies for early recognition of cutaneous melanoma—present and future
description	Cutaneous melanoma is a highly aggressive malignant tumor of skin melanocytes with an increasing incidence in most countries of the world, especially in the fair-skinned populations. Despite all preventive and therapeutic efforts, malignant melanoma is still the most lethal skin cancer. A delayed diagnosis results in an advanced stage and worsened prognosis. Once distant metastases are present, the five-year survival rate is less than 10 percent. At the same time, patients may be cured by an early diagnosis of cutaneous melanoma followed by a wide excision. Therefore, the early detection of melanoma at curable stages is crucial for the patients’ survival. Besides the investigation of pigmented lesions with the unaided eye, a wide range of examination techniques for improved diagnostic accuracy have been developed and validated in clinical trials. However, none of these techniques are able to provide a definite and final diagnosis or to replace an excisional biopsy of suspicious lesions followed by histological analysis. This review provides a concise overview of general principles as well as current and future strategies for an improved early diagnosis of cutaneous melanoma.
format	article
author	Franziska Brehmer Marina Ulrich Holger A. Haenssle
author_facet	Franziska Brehmer Marina Ulrich Holger A. Haenssle
author_sort	Franziska Brehmer
title	Strategies for early recognition of cutaneous melanoma—present and future
title_short	Strategies for early recognition of cutaneous melanoma—present and future
title_full	Strategies for early recognition of cutaneous melanoma—present and future
title_fullStr	Strategies for early recognition of cutaneous melanoma—present and future
title_full_unstemmed	Strategies for early recognition of cutaneous melanoma—present and future
title_sort	strategies for early recognition of cutaneous melanoma—present and future
publisher	Mattioli1885
publishDate	2012
url	https://doaj.org/article/eb93bcb9616b4eb5b97bd8f870938f69
work_keys_str_mv	AT franziskabrehmer strategiesforearlyrecognitionofcutaneousmelanomapresentandfuture AT marinaulrich strategiesforearlyrecognitionofcutaneousmelanomapresentandfuture AT holgerahaenssle strategiesforearlyrecognitionofcutaneousmelanomapresentandfuture
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Strategies for early recognition of cutaneous melanoma—present and future

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