Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.

Abstract Response surface methodology (RSM) including three variables was performed to optimize the extraction parameters of Astragalus cicer L. polysaccharides (ACPs). The influence of different drying techniques on the physicochemical properties and antioxidant abilities of ACPs were evaluated. Th...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hongmei Shang, Menghan Wang, Ran Li, Mengying Duan, Hongxin Wu, Haizhu Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/eb93cdfa35ec45d7a3e5c2f167454532
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eb93cdfa35ec45d7a3e5c2f167454532
record_format	dspace
spelling	oai:doaj.org-article:eb93cdfa35ec45d7a3e5c2f1674545322021-12-02T15:08:15ZExtraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.10.1038/s41598-018-21295-z2045-2322https://doaj.org/article/eb93cdfa35ec45d7a3e5c2f1674545322018-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-21295-zhttps://doaj.org/toc/2045-2322Abstract Response surface methodology (RSM) including three variables was performed to optimize the extraction parameters of Astragalus cicer L. polysaccharides (ACPs). The influence of different drying techniques on the physicochemical properties and antioxidant abilities of ACPs were evaluated. The ACPs were dried with hot air (HD), vacuum (VD) and freeze drying (FD) methods. The optimal conditions for ACPs extraction were as follows: water to raw material ratio of 25 mL/g, extraction time of 61 min and temperature of 75 °C. Under these parameters, an ACPs yield of 10.97% was obtained. HPLC analysis showed that the monosaccharide compositions of the three ACPs dried with HD, VD or FD techniques were identical. The three ACPs exhibited antioxidant abilities in a concentration-dependent manner. ACPs dried with the FD method (FD-ACPs) had the best antioxidant activities, which might be related to their smaller molecular weight and higher uronic acid content. At the determined concentration of 1 mg/mL, the ferric reducing power, and DPPH and ABTS free radical scavenging capacities of FD-ACPs were 0.762, 75.30% and 99.21%, respectively. Therefore, FD was a good choice for the drying of Astragalus cicer L. polysaccharides.Hongmei ShangMenghan WangRan LiMengying DuanHongxin WuHaizhu ZhouNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hongmei Shang Menghan Wang Ran Li Mengying Duan Hongxin Wu Haizhu Zhou Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
description	Abstract Response surface methodology (RSM) including three variables was performed to optimize the extraction parameters of Astragalus cicer L. polysaccharides (ACPs). The influence of different drying techniques on the physicochemical properties and antioxidant abilities of ACPs were evaluated. The ACPs were dried with hot air (HD), vacuum (VD) and freeze drying (FD) methods. The optimal conditions for ACPs extraction were as follows: water to raw material ratio of 25 mL/g, extraction time of 61 min and temperature of 75 °C. Under these parameters, an ACPs yield of 10.97% was obtained. HPLC analysis showed that the monosaccharide compositions of the three ACPs dried with HD, VD or FD techniques were identical. The three ACPs exhibited antioxidant abilities in a concentration-dependent manner. ACPs dried with the FD method (FD-ACPs) had the best antioxidant activities, which might be related to their smaller molecular weight and higher uronic acid content. At the determined concentration of 1 mg/mL, the ferric reducing power, and DPPH and ABTS free radical scavenging capacities of FD-ACPs were 0.762, 75.30% and 99.21%, respectively. Therefore, FD was a good choice for the drying of Astragalus cicer L. polysaccharides.
format	article
author	Hongmei Shang Menghan Wang Ran Li Mengying Duan Hongxin Wu Haizhu Zhou
author_facet	Hongmei Shang Menghan Wang Ran Li Mengying Duan Hongxin Wu Haizhu Zhou
author_sort	Hongmei Shang
title	Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
title_short	Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
title_full	Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
title_fullStr	Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
title_full_unstemmed	Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
title_sort	extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from astragalus cicer l.
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/eb93cdfa35ec45d7a3e5c2f167454532
work_keys_str_mv	AT hongmeishang extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl AT menghanwang extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl AT ranli extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl AT mengyingduan extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl AT hongxinwu extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl AT haizhuzhou extractionconditionoptimizationandeffectsofdryingmethodsonphysicochemicalpropertiesandantioxidantactivitiesofpolysaccharidesfromastragaluscicerl
_version_	1718388224903086080

Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.

Ejemplares similares