Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.
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Nature Portfolio
2021
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oai:doaj.org-article:eb977fb03c8d4446a9e5238f5e98ccbc2021-11-28T12:35:02ZImprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance10.1038/s41467-021-27171-12041-1723https://doaj.org/article/eb977fb03c8d4446a9e5238f5e98ccbc2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27171-1https://doaj.org/toc/2041-1723Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.Yan-Ting ChenQi-Yuan YangYun HuXiang-Dong LiuJeanene M. de AvilaMei-Jun ZhuPeter W. NathanielszMin DuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Yan-Ting Chen Qi-Yuan Yang Yun Hu Xiang-Dong Liu Jeanene M. de Avila Mei-Jun Zhu Peter W. Nathanielsz Min Du Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
description |
Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring. |
format |
article |
author |
Yan-Ting Chen Qi-Yuan Yang Yun Hu Xiang-Dong Liu Jeanene M. de Avila Mei-Jun Zhu Peter W. Nathanielsz Min Du |
author_facet |
Yan-Ting Chen Qi-Yuan Yang Yun Hu Xiang-Dong Liu Jeanene M. de Avila Mei-Jun Zhu Peter W. Nathanielsz Min Du |
author_sort |
Yan-Ting Chen |
title |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
title_short |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
title_full |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
title_fullStr |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
title_full_unstemmed |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance |
title_sort |
imprinted lncrna dio3os preprograms intergenerational brown fat development and obesity resistance |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/eb977fb03c8d4446a9e5238f5e98ccbc |
work_keys_str_mv |
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1718407927796072448 |