Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance

Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.

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Autores principales: Yan-Ting Chen, Qi-Yuan Yang, Yun Hu, Xiang-Dong Liu, Jeanene M. de Avila, Mei-Jun Zhu, Peter W. Nathanielsz, Min Du
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/eb977fb03c8d4446a9e5238f5e98ccbc
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spelling oai:doaj.org-article:eb977fb03c8d4446a9e5238f5e98ccbc2021-11-28T12:35:02ZImprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance10.1038/s41467-021-27171-12041-1723https://doaj.org/article/eb977fb03c8d4446a9e5238f5e98ccbc2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27171-1https://doaj.org/toc/2041-1723Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.Yan-Ting ChenQi-Yuan YangYun HuXiang-Dong LiuJeanene M. de AvilaMei-Jun ZhuPeter W. NathanielszMin DuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yan-Ting Chen
Qi-Yuan Yang
Yun Hu
Xiang-Dong Liu
Jeanene M. de Avila
Mei-Jun Zhu
Peter W. Nathanielsz
Min Du
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
description Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.
format article
author Yan-Ting Chen
Qi-Yuan Yang
Yun Hu
Xiang-Dong Liu
Jeanene M. de Avila
Mei-Jun Zhu
Peter W. Nathanielsz
Min Du
author_facet Yan-Ting Chen
Qi-Yuan Yang
Yun Hu
Xiang-Dong Liu
Jeanene M. de Avila
Mei-Jun Zhu
Peter W. Nathanielsz
Min Du
author_sort Yan-Ting Chen
title Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
title_short Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
title_full Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
title_fullStr Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
title_full_unstemmed Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
title_sort imprinted lncrna dio3os preprograms intergenerational brown fat development and obesity resistance
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/eb977fb03c8d4446a9e5238f5e98ccbc
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