Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature

Objective: To review the role of adjuvant hyperbaric oxygen therapy (HBOT) in the treatment of malignant otitis externa (MOE). Data sources: PubMed, Scopus, Web of Science, Science Direct, and Cochrane Library were searched for the following concepts: “hyperbaric oxygen” and “malignant or necrotizin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Young Jae Byun, Jaimin Patel, Shaun A. Nguyen, Paul R. Lambert
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2021
Materias:	Malignant otitis externa Necrotizing otitis externa Diabetes mellitus Hyperbaric oxygen Therapy Osteomyelitis Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/eba1afb3b831412991cc798301386733
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eba1afb3b831412991cc798301386733
record_format	dspace
spelling	oai:doaj.org-article:eba1afb3b831412991cc7983013867332021-12-02T15:13:59ZHyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature2095-881110.1016/j.wjorl.2020.04.002https://doaj.org/article/eba1afb3b831412991cc7983013867332021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881120300342https://doaj.org/toc/2095-8811Objective: To review the role of adjuvant hyperbaric oxygen therapy (HBOT) in the treatment of malignant otitis externa (MOE). Data sources: PubMed, Scopus, Web of Science, Science Direct, and Cochrane Library were searched for the following concepts: “hyperbaric oxygen” and “malignant or necrotizing otitis externa.” Methods: Studies were included if they contained (1) patients with reported evidence of MOE, (2) employment of adjuvant HBOT, (3) details on patients’ medical condition, and (4) documented survival outcomes. Extracted information included patient demographics, underlying medical conditions, infectious etiology, signs and symptoms, medical and surgical treatments, duration of medical treatment, mean follow up time, HBOT setting, number of HBOT sessions, complications, survival rate, and all-cause mortality. Results: A total of 16 studies comprising 58 patients (mean age 68.0 years) were included. Diabetes was present in 94.7% of cases and Pseudomonas spp (64.3%) was the most common infectious agent. Cranial nerve VII was involved in 55.2% of cases. Overall, the disease cure rate with adjuvant HBOT was 91.4% and all-cause mortality was 8.6%. Among those who had cranial nerve VII involvement, 72.0% had return of function and 93.8% of them survived. Conclusion: HBOT may be an effective treatment option for refractory or advanced MOE but its efficacy remains unproven due to lack of strong scientific evidence. However, its therapeutic value should not be underestimated given good results and few adverse events reported in this study.Young Jae ByunJaimin PatelShaun A. NguyenPaul R. LambertKeAi Communications Co., Ltd.articleMalignant otitis externaNecrotizing otitis externaDiabetes mellitusHyperbaric oxygenTherapyOsteomyelitisOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 4, Pp 296-302 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Malignant otitis externa Necrotizing otitis externa Diabetes mellitus Hyperbaric oxygen Therapy Osteomyelitis Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Malignant otitis externa Necrotizing otitis externa Diabetes mellitus Hyperbaric oxygen Therapy Osteomyelitis Otorhinolaryngology RF1-547 Surgery RD1-811 Young Jae Byun Jaimin Patel Shaun A. Nguyen Paul R. Lambert Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
description	Objective: To review the role of adjuvant hyperbaric oxygen therapy (HBOT) in the treatment of malignant otitis externa (MOE). Data sources: PubMed, Scopus, Web of Science, Science Direct, and Cochrane Library were searched for the following concepts: “hyperbaric oxygen” and “malignant or necrotizing otitis externa.” Methods: Studies were included if they contained (1) patients with reported evidence of MOE, (2) employment of adjuvant HBOT, (3) details on patients’ medical condition, and (4) documented survival outcomes. Extracted information included patient demographics, underlying medical conditions, infectious etiology, signs and symptoms, medical and surgical treatments, duration of medical treatment, mean follow up time, HBOT setting, number of HBOT sessions, complications, survival rate, and all-cause mortality. Results: A total of 16 studies comprising 58 patients (mean age 68.0 years) were included. Diabetes was present in 94.7% of cases and Pseudomonas spp (64.3%) was the most common infectious agent. Cranial nerve VII was involved in 55.2% of cases. Overall, the disease cure rate with adjuvant HBOT was 91.4% and all-cause mortality was 8.6%. Among those who had cranial nerve VII involvement, 72.0% had return of function and 93.8% of them survived. Conclusion: HBOT may be an effective treatment option for refractory or advanced MOE but its efficacy remains unproven due to lack of strong scientific evidence. However, its therapeutic value should not be underestimated given good results and few adverse events reported in this study.
format	article
author	Young Jae Byun Jaimin Patel Shaun A. Nguyen Paul R. Lambert
author_facet	Young Jae Byun Jaimin Patel Shaun A. Nguyen Paul R. Lambert
author_sort	Young Jae Byun
title	Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
title_short	Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
title_full	Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
title_fullStr	Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
title_full_unstemmed	Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature
title_sort	hyperbaric oxygen therapy in malignant otitis externa: a systematic review of the literature
publisher	KeAi Communications Co., Ltd.
publishDate	2021
url	https://doaj.org/article/eba1afb3b831412991cc798301386733
work_keys_str_mv	AT youngjaebyun hyperbaricoxygentherapyinmalignantotitisexternaasystematicreviewoftheliterature AT jaiminpatel hyperbaricoxygentherapyinmalignantotitisexternaasystematicreviewoftheliterature AT shaunanguyen hyperbaricoxygentherapyinmalignantotitisexternaasystematicreviewoftheliterature AT paulrlambert hyperbaricoxygentherapyinmalignantotitisexternaasystematicreviewoftheliterature
_version_	1718387604951400448

Hyperbaric oxygen therapy in malignant otitis externa: A systematic review of the literature

Ejemplares similares