Tripartite assembly of RND multidrug efflux pumps
Tripartite efflux systems consist of inner membrane, outer membrane and periplasmic components. Here, Daury et al. reconstitute native versions of RND transporters in nanodiscs and present projection structures emphasizing the role of the periplasmic adaptor in linking the inner and outer membrane p...
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Nature Portfolio
2016
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oai:doaj.org-article:eba793de8123457e92c40e3142a2ad4f2021-12-02T15:34:53ZTripartite assembly of RND multidrug efflux pumps10.1038/ncomms107312041-1723https://doaj.org/article/eba793de8123457e92c40e3142a2ad4f2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10731https://doaj.org/toc/2041-1723Tripartite efflux systems consist of inner membrane, outer membrane and periplasmic components. Here, Daury et al. reconstitute native versions of RND transporters in nanodiscs and present projection structures emphasizing the role of the periplasmic adaptor in linking the inner and outer membrane proteins.Laetitia DauryFrançois OrangeJean-Christophe TaveauAlice VerchèreLaura MonlezunCéline GounouRavi K. R. MarreddyMartin PicardIsabelle BroutinKlaas M. PosOlivier LambertNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Laetitia Daury François Orange Jean-Christophe Taveau Alice Verchère Laura Monlezun Céline Gounou Ravi K. R. Marreddy Martin Picard Isabelle Broutin Klaas M. Pos Olivier Lambert Tripartite assembly of RND multidrug efflux pumps |
description |
Tripartite efflux systems consist of inner membrane, outer membrane and periplasmic components. Here, Daury et al. reconstitute native versions of RND transporters in nanodiscs and present projection structures emphasizing the role of the periplasmic adaptor in linking the inner and outer membrane proteins. |
format |
article |
author |
Laetitia Daury François Orange Jean-Christophe Taveau Alice Verchère Laura Monlezun Céline Gounou Ravi K. R. Marreddy Martin Picard Isabelle Broutin Klaas M. Pos Olivier Lambert |
author_facet |
Laetitia Daury François Orange Jean-Christophe Taveau Alice Verchère Laura Monlezun Céline Gounou Ravi K. R. Marreddy Martin Picard Isabelle Broutin Klaas M. Pos Olivier Lambert |
author_sort |
Laetitia Daury |
title |
Tripartite assembly of RND multidrug efflux pumps |
title_short |
Tripartite assembly of RND multidrug efflux pumps |
title_full |
Tripartite assembly of RND multidrug efflux pumps |
title_fullStr |
Tripartite assembly of RND multidrug efflux pumps |
title_full_unstemmed |
Tripartite assembly of RND multidrug efflux pumps |
title_sort |
tripartite assembly of rnd multidrug efflux pumps |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/eba793de8123457e92c40e3142a2ad4f |
work_keys_str_mv |
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1718386753778221056 |