Lepirudin in the management of patients with heparin-induced thrombocytopenia

Sirak PetrosDepartment of Internal Medicine, University of Leipzig, Leipzig, GermanyAbstract: Lepirudin, a recombinant hirudin, is a direct irreversible thrombin inhibitor by binding to both free and clot-bound thrombin. It is approved for treatment of heparin-induced thrombocytopenia (HIT), which i...

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Auteur principal: Sirak Petros
Format: article
Langue:EN
Publié: Dove Medical Press 2008
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Accès en ligne:https://doaj.org/article/ebaa264c7d5c473a93f13071d9ab3ce4
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