IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+ T cells

Abstract Differentiation of regulatory Treg (Treg) in the periphery is critical to control inflammatory processes. Although polarization of inducible Treg (iTreg) often occurs in an inflammatory environment, the effects exerted by inflammation on human iTreg differentiation have not been extensively...

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Autores principales: Lea M. Feldhoff, Cesar M. Rueda, Maria E. Moreno-Fernandez, Johanna Sauer, Courtney M. Jackson, Claire A. Chougnet, Jan Rupp
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ebb9d13629594450a5de8b26a4278e2c
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