UPF2 is a critical regulator of liver development, function and regeneration.

<h4>Background</h4>Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction of mRNAs bearing premature terminations codons (PTCs). Such PTC-containing (PTC+) mRNAs may arise from different processes, including...

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Autores principales: Lina A Thoren, Gitte A Nørgaard, Joachim Weischenfeldt, Johannes Waage, Janus S Jakobsen, Inge Damgaard, Frida C Bergström, Anna M Blom, Rehannah Borup, Hanne Cathrine Bisgaard, Bo T Porse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/ebbde6b63c394befb3c39ee3b7590405
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