Interaction of Spike protein and lipid membrane of SARS-CoV-2 with Ursodeoxycholic acid, an in-silico analysis

Interaction of Spike protein and lipid membrane of SARS-CoV-2 with Ursodeoxycholic acid, an in-silico analysis

Abstract Numerous repositioned drugs have been sought to decrease the severity of SARS-CoV-2 infection. It is known that among its physicochemical properties, Ursodeoxycholic Acid (UDCA) has a reduction in surface tension and cholesterol solubilization, it has also been used to treat cholesterol gal...

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Autores principales: Francisco Javier Rodal Canales, Laura Pérez-Campos Mayoral, María Teresa Hernández-Huerta, Luis Manuel Sánchez Navarro, Carlos Alberto Matias-Cervantes, Margarito Martínez Cruz, Eli Cruz Parada, Edgar Zenteno, Edgar Gustavo Ramos-Martínez, Eduardo Pérez-Campos Mayoral, Carlos Romero Díaz, Eduardo Pérez-Campos
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ebc24283ec4d4507acac87d0ed56444c
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