Thyrotoxic periodic paralysis after urethral dilatation

Thyrotoxic periodic paralysis (TPP) is a rare and serious manifestation of thyrotoxicosis that causes flaccid paralysis. In severe cases, it can be life-threatening due to respiratory failure and cardiac arrhythmias. TPP is due to increased sodium/potassium ATPase activity during thyrotoxic states,...

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Autores principales:	Moayyad Alziadat, Mourad Ismail
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Materias:	hypokalemia paralysis periodic thyrotoxic thyrotoxicosis Medicine R
Acceso en línea:	https://doaj.org/article/ebc8af4841be41b4ad8f530dc36dec33
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spelling	oai:doaj.org-article:ebc8af4841be41b4ad8f530dc36dec332021-12-02T15:06:48ZThyrotoxic periodic paralysis after urethral dilatation2231-07702249-446410.4103/ajm.ajm_54_20https://doaj.org/article/ebc8af4841be41b4ad8f530dc36dec332020-10-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.ajm_54_20https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Thyrotoxic periodic paralysis (TPP) is a rare and serious manifestation of thyrotoxicosis that causes flaccid paralysis. In severe cases, it can be life-threatening due to respiratory failure and cardiac arrhythmias. TPP is due to increased sodium/potassium ATPase activity during thyrotoxic states, which is due to mutations encoding potassium channels. It is precipitated by situations that cause a surge in catecholamines, insulin, or both. It can be treated with potassium supplementation and nonselective beta blockers, and it can be prevented by establishing euthyroid state. With the increasing numbers of outpatient procedures performed nowadays and the stress related to these procedures, patients with TPP may develop paralysis after these procedures, so clinicians should be aware of this condition and the importance of identifying it in patients presenting with flaccid paralysis.Moayyad AlziadatMourad IsmailThieme Medical and Scientific Publishers Pvt. Ltd.articlehypokalemiaparalysisperiodicthyrotoxicthyrotoxicosisMedicineRENAvicenna Journal of Medicine, Vol 10, Iss 04, Pp 249-251 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hypokalemia paralysis periodic thyrotoxic thyrotoxicosis Medicine R
spellingShingle	hypokalemia paralysis periodic thyrotoxic thyrotoxicosis Medicine R Moayyad Alziadat Mourad Ismail Thyrotoxic periodic paralysis after urethral dilatation
description	Thyrotoxic periodic paralysis (TPP) is a rare and serious manifestation of thyrotoxicosis that causes flaccid paralysis. In severe cases, it can be life-threatening due to respiratory failure and cardiac arrhythmias. TPP is due to increased sodium/potassium ATPase activity during thyrotoxic states, which is due to mutations encoding potassium channels. It is precipitated by situations that cause a surge in catecholamines, insulin, or both. It can be treated with potassium supplementation and nonselective beta blockers, and it can be prevented by establishing euthyroid state. With the increasing numbers of outpatient procedures performed nowadays and the stress related to these procedures, patients with TPP may develop paralysis after these procedures, so clinicians should be aware of this condition and the importance of identifying it in patients presenting with flaccid paralysis.
format	article
author	Moayyad Alziadat Mourad Ismail
author_facet	Moayyad Alziadat Mourad Ismail
author_sort	Moayyad Alziadat
title	Thyrotoxic periodic paralysis after urethral dilatation
title_short	Thyrotoxic periodic paralysis after urethral dilatation
title_full	Thyrotoxic periodic paralysis after urethral dilatation
title_fullStr	Thyrotoxic periodic paralysis after urethral dilatation
title_full_unstemmed	Thyrotoxic periodic paralysis after urethral dilatation
title_sort	thyrotoxic periodic paralysis after urethral dilatation
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2020
url	https://doaj.org/article/ebc8af4841be41b4ad8f530dc36dec33
work_keys_str_mv	AT moayyadalziadat thyrotoxicperiodicparalysisafterurethraldilatation AT mouradismail thyrotoxicperiodicparalysisafterurethraldilatation
_version_	1718388487374241792

Thyrotoxic periodic paralysis after urethral dilatation

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