Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy

The dramatic increase in the number of patients with diabetes mellitus (DM) and chronic renal disease (CRD) in the recent years emphasizes the closeassociation between the two conditions and the leading role of DM in the development of renal pathology. Diabetology and nephrology are highly costlybra...

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Autores principales: Marina Vladimirovna Shestakova, Minara Shamkhalovna Shamkhalova, Ivona Yanovna Yarek-Martynova, Inna Igorevna Klefortova, Olga Yur'evna Sukhareva, Olga Konstantinovna Vikulova, Natalya Vladislavovna Zaytseva, Sergey Andreevich Martynov, Malkhaz Viktorovich Kvaratskheliya, Evgeny Vladimirovich Tarasov, Natalya Petrovna Trubitsyna
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RU
Publicado: Endocrinology Research Centre 2011
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Acceso en línea:https://doaj.org/article/ebcafd064c0e4d8b829b1a63ca7283fd
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spelling oai:doaj.org-article:ebcafd064c0e4d8b829b1a63ca7283fd2021-11-14T09:00:15ZDiabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy2072-03512072-037810.14341/2072-0351-6254https://doaj.org/article/ebcafd064c0e4d8b829b1a63ca7283fd2011-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6254https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378The dramatic increase in the number of patients with diabetes mellitus (DM) and chronic renal disease (CRD) in the recent years emphasizes the closeassociation between the two conditions and the leading role of DM in the development of renal pathology. Diabetology and nephrology are highly costlybranches of public health, and the burden of substitution renal therapy in DM patients continues to grow. The necessity of a renoprotection programat the early stages of DM for the prevention or delay of terminal renal insufficiency becomes increasingly clear. Such program should be based on theconceptual model of the evolvement of diabetic nephropathy as a consequence of combined action of metabolic and hemodynamic factors modulatedby genetic ones.Marina Vladimirovna ShestakovaMinara Shamkhalovna ShamkhalovaIvona Yanovna Yarek-MartynovaInna Igorevna KlefortovaOlga Yur'evna SukharevaOlga Konstantinovna VikulovaNatalya Vladislavovna ZaytsevaSergey Andreevich MartynovMalkhaz Viktorovich KvaratskheliyaEvgeny Vladimirovich TarasovNatalya Petrovna TrubitsynaEndocrinology Research Centrearticlediabetes mellituschronic kidney diseasediabetic nephropathyrenoprotectionNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 1, Pp 81-88 (2011)
institution DOAJ
collection DOAJ
language EN
RU
topic diabetes mellitus
chronic kidney disease
diabetic nephropathy
renoprotection
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle diabetes mellitus
chronic kidney disease
diabetic nephropathy
renoprotection
Nutritional diseases. Deficiency diseases
RC620-627
Marina Vladimirovna Shestakova
Minara Shamkhalovna Shamkhalova
Ivona Yanovna Yarek-Martynova
Inna Igorevna Klefortova
Olga Yur'evna Sukhareva
Olga Konstantinovna Vikulova
Natalya Vladislavovna Zaytseva
Sergey Andreevich Martynov
Malkhaz Viktorovich Kvaratskheliya
Evgeny Vladimirovich Tarasov
Natalya Petrovna Trubitsyna
Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
description The dramatic increase in the number of patients with diabetes mellitus (DM) and chronic renal disease (CRD) in the recent years emphasizes the closeassociation between the two conditions and the leading role of DM in the development of renal pathology. Diabetology and nephrology are highly costlybranches of public health, and the burden of substitution renal therapy in DM patients continues to grow. The necessity of a renoprotection programat the early stages of DM for the prevention or delay of terminal renal insufficiency becomes increasingly clear. Such program should be based on theconceptual model of the evolvement of diabetic nephropathy as a consequence of combined action of metabolic and hemodynamic factors modulatedby genetic ones.
format article
author Marina Vladimirovna Shestakova
Minara Shamkhalovna Shamkhalova
Ivona Yanovna Yarek-Martynova
Inna Igorevna Klefortova
Olga Yur'evna Sukhareva
Olga Konstantinovna Vikulova
Natalya Vladislavovna Zaytseva
Sergey Andreevich Martynov
Malkhaz Viktorovich Kvaratskheliya
Evgeny Vladimirovich Tarasov
Natalya Petrovna Trubitsyna
author_facet Marina Vladimirovna Shestakova
Minara Shamkhalovna Shamkhalova
Ivona Yanovna Yarek-Martynova
Inna Igorevna Klefortova
Olga Yur'evna Sukhareva
Olga Konstantinovna Vikulova
Natalya Vladislavovna Zaytseva
Sergey Andreevich Martynov
Malkhaz Viktorovich Kvaratskheliya
Evgeny Vladimirovich Tarasov
Natalya Petrovna Trubitsyna
author_sort Marina Vladimirovna Shestakova
title Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
title_short Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
title_full Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
title_fullStr Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
title_full_unstemmed Diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
title_sort diabetes mellitus and chronic kidney disease: achievements, unresolved problems, and prospects for therapy
publisher Endocrinology Research Centre
publishDate 2011
url https://doaj.org/article/ebcafd064c0e4d8b829b1a63ca7283fd
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