Diagnosis and screening of patients with generalized pustular psoriasis

Karen Ly,* Kristen M Beck*, Mary P Smith, Quinn Thibodeaux, Tina BhutaniDepartment of Dermatology, University of California, San Francisco, CA, USA*These authors contributed equally to this work Abstract: Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening variant of psor...

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Autores principales:	Ly K, Beck KM, Smith MP, Thibodeaux Q, Bhutani T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	generalized pustular psoriasis von Zumbusch pustular psoriasis diagnostic criteria Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/ebfc18d1c295407482c8bd774f959061
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spelling	oai:doaj.org-article:ebfc18d1c295407482c8bd774f9590612021-12-02T06:43:15ZDiagnosis and screening of patients with generalized pustular psoriasis2230-326Xhttps://doaj.org/article/ebfc18d1c295407482c8bd774f9590612019-06-01T00:00:00Zhttps://www.dovepress.com/diagnosis-and-screening-of-patients-with-generalized-pustular-psoriasi-peer-reviewed-article-PTThttps://doaj.org/toc/2230-326XKaren Ly,* Kristen M Beck, Mary P Smith, Quinn Thibodeaux, Tina BhutaniDepartment of Dermatology, University of California, San Francisco, CA, USAThese authors contributed equally to this work Abstract: Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening variant of psoriasis that is characterized by recurrent, acute onset, widely distributed pustular eruptions on inflamed, erythematous skin. It is important to recognize acute GPP as a subtype of psoriasis associated with high morbidity and mortality so therapy can be initiated without delay. Since GPP was first described in 1910 by Leopold von Zumbusch, it has been inconsistently defined, stratified, and diagnosed in the literature. Multiple definitions and diagnostic criteria have been proposed over the years. Recently, formal consensus guidelines on GPP have been published by international groups. This article reviews the current evidence and understanding in the diagnosis and screening of GPP.Keywords: generalized pustular psoriasis, acute generalized pustular psoriasis of von Zumbusch, pustular psoriasis, diagnostic criteriaLy KBeck KMSmith MPThibodeaux QBhutani TDove Medical Pressarticlegeneralized pustular psoriasisvon Zumbuschpustular psoriasisdiagnostic criteriaDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol Volume 9, Pp 37-42 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	generalized pustular psoriasis von Zumbusch pustular psoriasis diagnostic criteria Dermatology RL1-803
spellingShingle	generalized pustular psoriasis von Zumbusch pustular psoriasis diagnostic criteria Dermatology RL1-803 Ly K Beck KM Smith MP Thibodeaux Q Bhutani T Diagnosis and screening of patients with generalized pustular psoriasis
description	Karen Ly,* Kristen M Beck, Mary P Smith, Quinn Thibodeaux, Tina BhutaniDepartment of Dermatology, University of California, San Francisco, CA, USAThese authors contributed equally to this work Abstract: Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening variant of psoriasis that is characterized by recurrent, acute onset, widely distributed pustular eruptions on inflamed, erythematous skin. It is important to recognize acute GPP as a subtype of psoriasis associated with high morbidity and mortality so therapy can be initiated without delay. Since GPP was first described in 1910 by Leopold von Zumbusch, it has been inconsistently defined, stratified, and diagnosed in the literature. Multiple definitions and diagnostic criteria have been proposed over the years. Recently, formal consensus guidelines on GPP have been published by international groups. This article reviews the current evidence and understanding in the diagnosis and screening of GPP.Keywords: generalized pustular psoriasis, acute generalized pustular psoriasis of von Zumbusch, pustular psoriasis, diagnostic criteria
format	article
author	Ly K Beck KM Smith MP Thibodeaux Q Bhutani T
author_facet	Ly K Beck KM Smith MP Thibodeaux Q Bhutani T
author_sort	Ly K
title	Diagnosis and screening of patients with generalized pustular psoriasis
title_short	Diagnosis and screening of patients with generalized pustular psoriasis
title_full	Diagnosis and screening of patients with generalized pustular psoriasis
title_fullStr	Diagnosis and screening of patients with generalized pustular psoriasis
title_full_unstemmed	Diagnosis and screening of patients with generalized pustular psoriasis
title_sort	diagnosis and screening of patients with generalized pustular psoriasis
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/ebfc18d1c295407482c8bd774f959061
work_keys_str_mv	AT lyk diagnosisandscreeningofpatientswithgeneralizedpustularpsoriasis AT beckkm diagnosisandscreeningofpatientswithgeneralizedpustularpsoriasis AT smithmp diagnosisandscreeningofpatientswithgeneralizedpustularpsoriasis AT thibodeauxq diagnosisandscreeningofpatientswithgeneralizedpustularpsoriasis AT bhutanit diagnosisandscreeningofpatientswithgeneralizedpustularpsoriasis
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Diagnosis and screening of patients with generalized pustular psoriasis

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