RTEL1 influences the abundance and localization of TERRA RNA

Long non coding RNA TERRA transcripts can form R-loops at chromosome ends. Here, the authors reveal a role for the helicase RTEL in affecting TERRA levels and localization.

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Autores principales: Fiorella Ghisays, Aitor Garzia, Hexiao Wang, Claudia Canasto-Chibuque, Marcel Hohl, Sharon A. Savage, Thomas Tuschl, John H. J. Petrini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ebfd9118102c4c7cb6a997e959f8aefb
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spelling oai:doaj.org-article:ebfd9118102c4c7cb6a997e959f8aefb2021-12-02T15:45:24ZRTEL1 influences the abundance and localization of TERRA RNA10.1038/s41467-021-23299-22041-1723https://doaj.org/article/ebfd9118102c4c7cb6a997e959f8aefb2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23299-2https://doaj.org/toc/2041-1723Long non coding RNA TERRA transcripts can form R-loops at chromosome ends. Here, the authors reveal a role for the helicase RTEL in affecting TERRA levels and localization.Fiorella GhisaysAitor GarziaHexiao WangClaudia Canasto-ChibuqueMarcel HohlSharon A. SavageThomas TuschlJohn H. J. PetriniNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fiorella Ghisays
Aitor Garzia
Hexiao Wang
Claudia Canasto-Chibuque
Marcel Hohl
Sharon A. Savage
Thomas Tuschl
John H. J. Petrini
RTEL1 influences the abundance and localization of TERRA RNA
description Long non coding RNA TERRA transcripts can form R-loops at chromosome ends. Here, the authors reveal a role for the helicase RTEL in affecting TERRA levels and localization.
format article
author Fiorella Ghisays
Aitor Garzia
Hexiao Wang
Claudia Canasto-Chibuque
Marcel Hohl
Sharon A. Savage
Thomas Tuschl
John H. J. Petrini
author_facet Fiorella Ghisays
Aitor Garzia
Hexiao Wang
Claudia Canasto-Chibuque
Marcel Hohl
Sharon A. Savage
Thomas Tuschl
John H. J. Petrini
author_sort Fiorella Ghisays
title RTEL1 influences the abundance and localization of TERRA RNA
title_short RTEL1 influences the abundance and localization of TERRA RNA
title_full RTEL1 influences the abundance and localization of TERRA RNA
title_fullStr RTEL1 influences the abundance and localization of TERRA RNA
title_full_unstemmed RTEL1 influences the abundance and localization of TERRA RNA
title_sort rtel1 influences the abundance and localization of terra rna
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ebfd9118102c4c7cb6a997e959f8aefb
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