Mapping the perturbome network of cellular perturbations

Our understanding of the mechanisms of drug interactions remains limited. Here the authors introduce a framework to study how complex cellular perturbations induced by different drugs affect each other in morphological feature space.

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Autores principales:	Michael Caldera, Felix Müller, Isabel Kaltenbrunner, Marco P. Licciardello, Charles-Hugues Lardeau, Stefan Kubicek, Jörg Menche
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ec05038356674ee18e5720f332d66c81
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spelling	oai:doaj.org-article:ec05038356674ee18e5720f332d66c812021-12-02T16:58:29ZMapping the perturbome network of cellular perturbations10.1038/s41467-019-13058-92041-1723https://doaj.org/article/ec05038356674ee18e5720f332d66c812019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13058-9https://doaj.org/toc/2041-1723Our understanding of the mechanisms of drug interactions remains limited. Here the authors introduce a framework to study how complex cellular perturbations induced by different drugs affect each other in morphological feature space.Michael CalderaFelix MüllerIsabel KaltenbrunnerMarco P. LicciardelloCharles-Hugues LardeauStefan KubicekJörg MencheNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael Caldera Felix Müller Isabel Kaltenbrunner Marco P. Licciardello Charles-Hugues Lardeau Stefan Kubicek Jörg Menche Mapping the perturbome network of cellular perturbations
description	Our understanding of the mechanisms of drug interactions remains limited. Here the authors introduce a framework to study how complex cellular perturbations induced by different drugs affect each other in morphological feature space.
format	article
author	Michael Caldera Felix Müller Isabel Kaltenbrunner Marco P. Licciardello Charles-Hugues Lardeau Stefan Kubicek Jörg Menche
author_facet	Michael Caldera Felix Müller Isabel Kaltenbrunner Marco P. Licciardello Charles-Hugues Lardeau Stefan Kubicek Jörg Menche
author_sort	Michael Caldera
title	Mapping the perturbome network of cellular perturbations
title_short	Mapping the perturbome network of cellular perturbations
title_full	Mapping the perturbome network of cellular perturbations
title_fullStr	Mapping the perturbome network of cellular perturbations
title_full_unstemmed	Mapping the perturbome network of cellular perturbations
title_sort	mapping the perturbome network of cellular perturbations
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ec05038356674ee18e5720f332d66c81
work_keys_str_mv	AT michaelcaldera mappingtheperturbomenetworkofcellularperturbations AT felixmuller mappingtheperturbomenetworkofcellularperturbations AT isabelkaltenbrunner mappingtheperturbomenetworkofcellularperturbations AT marcoplicciardello mappingtheperturbomenetworkofcellularperturbations AT charleshugueslardeau mappingtheperturbomenetworkofcellularperturbations AT stefankubicek mappingtheperturbomenetworkofcellularperturbations AT jorgmenche mappingtheperturbomenetworkofcellularperturbations
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Mapping the perturbome network of cellular perturbations

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