Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers
Paul C Edwards1, John E Fantasia21Associate Professor (Clinical), Department of Periodontics and Oral Medicine, Pathology and Oncology, University of Michigan School of Dentistry, Ann Arbor MI, USA; 2Chief, Division of Oral Pathology, Department of Dental Medicine, Long Island Jewish Medical Center,...
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Dove Medical Press
2008
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oai:doaj.org-article:ec0a82d9740f48139c9e4d8d3725e4522021-12-02T00:32:53ZReview of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers1178-1998https://doaj.org/article/ec0a82d9740f48139c9e4d8d3725e4522008-01-01T00:00:00Zhttps://www.dovepress.com/review-of-long-term-adverse-effects-associated-with-the-use-of-chemica-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Paul C Edwards1, John E Fantasia21Associate Professor (Clinical), Department of Periodontics and Oral Medicine, Pathology and Oncology, University of Michigan School of Dentistry, Ann Arbor MI, USA; 2Chief, Division of Oral Pathology, Department of Dental Medicine, Long Island Jewish Medical Center, New Hyde Park, NY, USAAbstract: Although only recently introduced, chemically-modified hyaluronic acid dermal fillers have gained widespread acceptance as “redefining” dermal fillers in the fields of dermatology and cosmetic facial surgery. Although hyaluronic acid-based dermal fillers have a low overall incidence of long term side effects, occasional adverse outcomes, ranging from chronic lymphoplasmacytic inflammatory reactions to classic foreign body-type granulomatous reactions have been documented. These long-term adverse events are reviewed.Keywords: hyaluronic acid, Restylane®, Hylaform®, injectable dermal filler, foreign body reaction, granulomaPaul C EdwardsJohn E FantasiaDove Medical PressarticleGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 2, Pp 509-519 (2008) |
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Geriatrics RC952-954.6 Paul C Edwards John E Fantasia Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
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Paul C Edwards1, John E Fantasia21Associate Professor (Clinical), Department of Periodontics and Oral Medicine, Pathology and Oncology, University of Michigan School of Dentistry, Ann Arbor MI, USA; 2Chief, Division of Oral Pathology, Department of Dental Medicine, Long Island Jewish Medical Center, New Hyde Park, NY, USAAbstract: Although only recently introduced, chemically-modified hyaluronic acid dermal fillers have gained widespread acceptance as “redefining” dermal fillers in the fields of dermatology and cosmetic facial surgery. Although hyaluronic acid-based dermal fillers have a low overall incidence of long term side effects, occasional adverse outcomes, ranging from chronic lymphoplasmacytic inflammatory reactions to classic foreign body-type granulomatous reactions have been documented. These long-term adverse events are reviewed.Keywords: hyaluronic acid, Restylane®, Hylaform®, injectable dermal filler, foreign body reaction, granuloma |
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article |
author |
Paul C Edwards John E Fantasia |
author_facet |
Paul C Edwards John E Fantasia |
author_sort |
Paul C Edwards |
title |
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
title_short |
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
title_full |
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
title_fullStr |
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
title_full_unstemmed |
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
title_sort |
review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/ec0a82d9740f48139c9e4d8d3725e452 |
work_keys_str_mv |
AT paulcedwards reviewoflongtermadverseeffectsassociatedwiththeuseofchemicallymodifiedanimalandnonanimalsourcehyaluronicaciddermalfillers AT johnefantasia reviewoflongtermadverseeffectsassociatedwiththeuseofchemicallymodifiedanimalandnonanimalsourcehyaluronicaciddermalfillers |
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