Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)

The aim of the present study was to investigate the cellular characteristics of the immune tissues of Zebrafish, Danio rerio (Hamilton, 1822). The fish were fixed in Bouin՚s solution for 24 hours then dehydrated, cleared, paraffinized, embedded and finally sectioned, stained and observed through opt...

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Autores principales: Azar Azin, Khoshnood Zahra
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Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/ec16b00d10f3409a973b875551de1544
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spelling oai:doaj.org-article:ec16b00d10f3409a973b875551de15442021-12-05T14:11:11ZHistological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)2344-321910.2478/trser-2021-0011https://doaj.org/article/ec16b00d10f3409a973b875551de15442021-07-01T00:00:00Zhttps://doi.org/10.2478/trser-2021-0011https://doaj.org/toc/2344-3219The aim of the present study was to investigate the cellular characteristics of the immune tissues of Zebrafish, Danio rerio (Hamilton, 1822). The fish were fixed in Bouin՚s solution for 24 hours then dehydrated, cleared, paraffinized, embedded and finally sectioned, stained and observed through optical microscopy. Results showed that immune system tissues of Zebrafish include the apical part of the kidney, thymus, and spleen. The apical part of the kidney was composed of hematopoietic tissue containing blood and immune cells. The spleen was a single organ located at the abdominal cavity containing melanomacrophages. The thymus was observed as a paired organ at the posterior part of the branchial cavity. Results showed that the immune system of the Zebrafish was dispersed in several organs of the body and that this species could be used as a laboratory model organism in immune system studies.Azar AzinKhoshnood ZahraSciendoarticlezebrafishhistologyimmune systemEcologyQH540-549.5ENTransylvanian Review of Systematical and Ecological Research, Vol 23, Iss 2, Pp 21-28 (2021)
institution DOAJ
collection DOAJ
language EN
topic zebrafish
histology
immune system
Ecology
QH540-549.5
spellingShingle zebrafish
histology
immune system
Ecology
QH540-549.5
Azar Azin
Khoshnood Zahra
Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
description The aim of the present study was to investigate the cellular characteristics of the immune tissues of Zebrafish, Danio rerio (Hamilton, 1822). The fish were fixed in Bouin՚s solution for 24 hours then dehydrated, cleared, paraffinized, embedded and finally sectioned, stained and observed through optical microscopy. Results showed that immune system tissues of Zebrafish include the apical part of the kidney, thymus, and spleen. The apical part of the kidney was composed of hematopoietic tissue containing blood and immune cells. The spleen was a single organ located at the abdominal cavity containing melanomacrophages. The thymus was observed as a paired organ at the posterior part of the branchial cavity. Results showed that the immune system of the Zebrafish was dispersed in several organs of the body and that this species could be used as a laboratory model organism in immune system studies.
format article
author Azar Azin
Khoshnood Zahra
author_facet Azar Azin
Khoshnood Zahra
author_sort Azar Azin
title Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
title_short Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
title_full Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
title_fullStr Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
title_full_unstemmed Histological Study of the Immune System in Zebrafish, Danio Rerio (Hamilton, 1822)
title_sort histological study of the immune system in zebrafish, danio rerio (hamilton, 1822)
publisher Sciendo
publishDate 2021
url https://doaj.org/article/ec16b00d10f3409a973b875551de1544
work_keys_str_mv AT azarazin histologicalstudyoftheimmunesysteminzebrafishdanioreriohamilton1822
AT khoshnoodzahra histologicalstudyoftheimmunesysteminzebrafishdanioreriohamilton1822
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