The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype.
Indirect evidences suggest that acetylation phenotype categories are heterogeneous and that subcategories, related to specific NAT2 variant alleles might exist. We analyzed the in vivo acetylation phenotype and genotype in 504 north-American subjects of Caucasian origin. The analyses of the SNPs rs1...
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Auteurs principaux: | Jhon D Ruiz, Carmen Martínez, Kristin Anderson, Myron Gross, Nicholas P Lang, Elena García-Martín, José A G Agúndez |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/ec17d7d5fb914c7e8726e7cdbb14c69a |
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