Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing
Abstract Ceramide (Cer) release from glucosylceramides (GlcCer) is critical for the formation of the skin permeability barrier. Changes in β-glucocerebrosidase (GlcCer’ase) activity lead to diminished Cer, GlcCer accumulation and structural defects in SC lipid lamellae; however, the molecular basis...
Guardado en:
Autores principales: | Michaela Sochorová, Klára Staňková, Petra Pullmannová, Andrej Kováčik, Jarmila Zbytovská, Kateřina Vávrová |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ec2786da6eb34f7a8a0b6fe5e380cd79 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents
por: Leonie Wallmeyer, et al.
Publicado: (2017) -
Sitosterol and glucosylceramide cooperative transversal and lateral uneven distribution in plant membranes
por: V. Rondelli, et al.
Publicado: (2021) -
Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI
por: Young Eun Huh, et al.
Publicado: (2021) -
Correlation between the structure and skin permeability of compounds
por: Ruolan Zeng, et al.
Publicado: (2021) -
THE SKIN BARRIER IN SENSITIVE SKIN SYNDROME
por: Filka Georgieva
Publicado: (2021)