Effects of inoculation route and dose on production and avidity of IgY antibodies

The aim of this study was to investigate the effects of route of inoculation and dose on production and avidity of IgY antibodies in chickens. The animals were inoculated with 20 µg of human IgG by intramuscular, intradermal, or subcutaneous routes, or with 2, 20, or 200 µg of human IgG via IM to ev...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Michele Pagliari Oliveira Montini, Eduardo Vignoto Fernandes, Ana Carolina Navarro dos Santos Ferraro, Mayara Alencar Almeida, Fabiano Cardoso da Silva, Emerson José Venancio
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	immunisation immunoglobulin y egg yolk Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/ec2e6305241a4504a30128a0768908d1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ec2e6305241a4504a30128a0768908d1
record_format	dspace
spelling	oai:doaj.org-article:ec2e6305241a4504a30128a0768908d12021-11-26T11:19:46ZEffects of inoculation route and dose on production and avidity of IgY antibodies0954-01051465-344310.1080/09540105.2017.1376036https://doaj.org/article/ec2e6305241a4504a30128a0768908d12018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2017.1376036https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443The aim of this study was to investigate the effects of route of inoculation and dose on production and avidity of IgY antibodies in chickens. The animals were inoculated with 20 µg of human IgG by intramuscular, intradermal, or subcutaneous routes, or with 2, 20, or 200 µg of human IgG via IM to evaluate the effect of dose. All routes led to significant levels of specific antibodies after the fifth inoculation. There was a significant difference in the levels of antibodies produced with 2 and 200 µg of antigen after the third and seventh inoculation. It was observed that there is no influence of route of inoculation or dose on the avidity of the antibodies produced. Furthermore, the index of avidity is influenced directly by the number of inoculations. These results are important to help future studies where antibody production of IgY from laying hens is necessary.Michele Pagliari Oliveira MontiniEduardo Vignoto FernandesAna Carolina Navarro dos Santos FerraroMayara Alencar AlmeidaFabiano Cardoso da SilvaEmerson José VenancioTaylor & Francis Grouparticleimmunisationimmunoglobulin yegg yolkAgriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 306-315 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	immunisation immunoglobulin y egg yolk Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
spellingShingle	immunisation immunoglobulin y egg yolk Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Michele Pagliari Oliveira Montini Eduardo Vignoto Fernandes Ana Carolina Navarro dos Santos Ferraro Mayara Alencar Almeida Fabiano Cardoso da Silva Emerson José Venancio Effects of inoculation route and dose on production and avidity of IgY antibodies
description	The aim of this study was to investigate the effects of route of inoculation and dose on production and avidity of IgY antibodies in chickens. The animals were inoculated with 20 µg of human IgG by intramuscular, intradermal, or subcutaneous routes, or with 2, 20, or 200 µg of human IgG via IM to evaluate the effect of dose. All routes led to significant levels of specific antibodies after the fifth inoculation. There was a significant difference in the levels of antibodies produced with 2 and 200 µg of antigen after the third and seventh inoculation. It was observed that there is no influence of route of inoculation or dose on the avidity of the antibodies produced. Furthermore, the index of avidity is influenced directly by the number of inoculations. These results are important to help future studies where antibody production of IgY from laying hens is necessary.
format	article
author	Michele Pagliari Oliveira Montini Eduardo Vignoto Fernandes Ana Carolina Navarro dos Santos Ferraro Mayara Alencar Almeida Fabiano Cardoso da Silva Emerson José Venancio
author_facet	Michele Pagliari Oliveira Montini Eduardo Vignoto Fernandes Ana Carolina Navarro dos Santos Ferraro Mayara Alencar Almeida Fabiano Cardoso da Silva Emerson José Venancio
author_sort	Michele Pagliari Oliveira Montini
title	Effects of inoculation route and dose on production and avidity of IgY antibodies
title_short	Effects of inoculation route and dose on production and avidity of IgY antibodies
title_full	Effects of inoculation route and dose on production and avidity of IgY antibodies
title_fullStr	Effects of inoculation route and dose on production and avidity of IgY antibodies
title_full_unstemmed	Effects of inoculation route and dose on production and avidity of IgY antibodies
title_sort	effects of inoculation route and dose on production and avidity of igy antibodies
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/ec2e6305241a4504a30128a0768908d1
work_keys_str_mv	AT michelepagliarioliveiramontini effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies AT eduardovignotofernandes effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies AT anacarolinanavarrodossantosferraro effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies AT mayaraalencaralmeida effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies AT fabianocardosodasilva effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies AT emersonjosevenancio effectsofinoculationrouteanddoseonproductionandavidityofigyantibodies
_version_	1718409568809123840

Effects of inoculation route and dose on production and avidity of IgY antibodies

Ejemplares similares