Prioritizing and characterizing functionally relevant genes across human tissues.

Knowledge of genes that are critical to a tissue's function remains difficult to ascertain and presents a major bottleneck toward a mechanistic understanding of genotype-phenotype links. Here, we present the first machine learning model-FUGUE-combining transcriptional and network features, to p...

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Auteurs principaux: Gowthami Somepalli, Sarthak Sahoo, Arashdeep Singh, Sridhar Hannenhalli
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/ec34913d83af4be5b41ab61cfb9daf94
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